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MR/K002414/1

Funded outputs count: 30
Funder award ID: MR/K002414/1
OpenAlex ID: G478728645
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
2023 · Liam McAllan, Damir Baranasic, et al. · Nature Communications · 43
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Associations of autozygosity with a broad range of human phenotypes
2019 · David W Clark, Yukinori Okada, et al. · Nature Communications · 149
Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
2019 · Amy R. Bentley, Understanding Society Scientific Group, et al. · Nature Genetics · 123
A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
2019 · Yun Ju Sung, Lisa de las Fuentes, et al. · Human Molecular Genetics · 42
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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
2019 · Paul S de Vries, Michael R Brown, et al. · American Journal of Epidemiology · 115
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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
2018 · Symen Ligthart, Ahmad Vaez, et al. · The American Journal of Human Genetics · 419
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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
2018 · Mary F. Feitosa, Aldi T. Kraja, et al. · PLoS ONE · 1,165
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
2018 · Yun J. Sung, Thomas W. Winkler, et al. · The American Journal of Human Genetics · 163
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
2017 · Jason Flannick, Christian Fuchsberger, et al. · Scientific Data · 37
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Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
2017 · Eleanor Wheeler, Aaron Leong, et al. · PLoS Medicine · 408
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
2017 · Ioanna Tachmazidou, Dániel Süveges, et al. · The American Journal of Human Genetics · 191
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
2017 · Mariaelisa Graff, Robert A. Scott, et al. · PLoS Genetics · 329
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
2017 · Alisa Manning, Heather M. Highland, et al. · Diabetes · 50
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Rare and low-frequency coding variants alter human adult height
2017 · Eirini Marouli, Mariaelisa Graff, et al. · Nature · 609
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Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
2016 · Simone Wahl, Alexander Drong, et al. · Nature · 945
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Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels
2016 · Fredrik Jernerén, Benjamin C. Lehne, et al. · Thrombosis and Haemostasis · 8
The genetic architecture of type 2 diabetes
2016 · Christian Fuchsberger, Jason Flannick, et al. · Nature · 1,049
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Investigation of Genetic Variation Underlying Central Obesity amongst South Asians
2016 · William R. Scott, Weihua Zhang, et al. · PLoS ONE · 29
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Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels
2016 · Elisabeth M van Leeuwen, Aniko Sabo, et al. · Journal of Medical Genetics · 32
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
2016 · Yingchang Lu, Felix R. Day, et al. · Nature Communications · 289
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
2015 · Thomas W. Winkler, Anne E. Justice, et al. · PLoS Genetics · 662
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
2015 · Norihiro Kato, CARDIo GRAMplusCD, et al. · Nature Genetics · 364
Directional dominance on stature and cognition in diverse human populations
2015 · The BioBank Japan Project, Peter K. Joshi, et al. · Nature · 178
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Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
2015 · John C Chambers, Marie Loh, et al. · The Lancet Diabetes & Endocrinology · 510
A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
2015 · Benjamin Lehne, Alexander W Drong, et al. · Genome biology · 378
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