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DK 51050

Funded outputs count: 24
Funder award ID: DK 51050
OpenAlex ID: G479217668
Disruption of polycystin-L causes hippocampal and thalamocortical hyperexcitability
2015 · Gang Yao, Chong Luo, et al. · Human Molecular Genetics · 37
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
2015 · Benjamin S. Freedman, Craig R. Brooks, et al. · Nature Communications · 796
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Bardet–Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein
2014 · Xuefeng Su, Kaitlin Driscoll, et al. · Human Molecular Genetics · 79
L-type calcium channel modulates cystic kidney phenotype
2014 · Xingjian Jin, Brian S. Muntean, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 36
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Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex
2014 · G. Yao, X. Su, et al. · Human Molecular Genetics · 58
Reduced Ciliary Polycystin-2 in Induced Pluripotent Stem Cells from Polycystic Kidney Disease Patients with PKD1 Mutations
2013 · Benjamin S. Freedman, Albert Q. Lam, et al. · Journal of the American Society of Nephrology · 116
The cytoplasmic protein Pacsin 2 in kidney development and injury repair
2012 · Gang Yao, Annouck Luyten, et al. · Kidney International · 14
c-Met and NF-κB–Dependent Overexpression of Wnt7a and -7b and Pax2 Promotes Cystogenesis in Polycystic Kidney Disease
2012 · Shan Qin, Mary Taglienti, et al. · Journal of the American Society of Nephrology · 71
Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways
2011 · Ayumi Takakura, Erik A. Nelson, et al. · Human Molecular Genetics · 143
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Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease
2010 · Shan Qin, Mary Taglienti, et al. · Journal of Clinical Investigation · 71
Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease
2010 · Annouck Luyten, Xuefeng Su, et al. · Journal of the American Society of Nephrology · 117
Identification of Signaling Pathways Regulating Primary Cilium Length and Flow-Mediated Adaptation
2010 · Tatiana Y. Besschetnova, Elona Kolpakova-Hart, et al. · Current Biology · 343
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Renal injury is a third hit promoting rapid development of adult polycystic kidney disease
2009 · Ayumi Takakura, Leah Contrino, et al. · Human Molecular Genetics · 209
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Polycystins and Primary Cilia: Primers for Cell Cycle Progression
2009 · Jing Zhou · Annual Review of Physiology · 195
Pkd1 Inactivation Induced in Adulthood Produces Focal Cystic Disease
2008 · Ayumi Takakura, Leah Contrino, et al. · Journal of the American Society of Nephrology · 117
A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5′ end of Pkd1
2008 · P.G. Starremans, X. Li, et al. · Kidney International · 89
Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1
2008 · Surya M. Nauli, Yoshifumi Kawanabe, et al. · Circulation · 485
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Nek8 Regulates the Expression and Localization of Polycystin-1 and Polycystin-2
2008 · Eisei Sohara, Ying Luo, et al. · Journal of the American Society of Nephrology · 135
Loss of Polycystin-1 in Human Cyst-Lining Epithelia Leads to Ciliary Dysfunction
2006 · Surya M. Nauli, Sandro Rossetti, et al. · Journal of the American Society of Nephrology · 191
Polycystin-1 and polycystin-2 regulate the cell cycle through the helix–loop–helix inhibitor Id2
2005 · Xiaogang Li, Ying Luo, et al. · Nature Cell Biology · 221
Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes
1999 · Weining Lu, Xiaohong Fan, et al. · Nature Genetics · 162
Identification of PKDL, a Novel Polycystic Kidney Disease 2-Like Gene Whose Murine Homologue Is Deleted in Mice with Kidney and Retinal Defects
1998 · Hideki Nomura, Alberto E. Turco, et al. · Journal of Biological Chemistry · 162
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Distribution and developmentally regulated expression of murine polycystin
1997 · L. Geng, Y. Segal, et al. · American Journal of Physiology-Renal Physiology · 120
Identification and localization of polycystin, the PKD1 gene product.
1996 · L Geng, Y Segal, et al. · Journal of Clinical Investigation · 196
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