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Role of Endocytosis in Cell Recognition

Funding type: research
Funder scheme: R37
Start date: 1986-01-01
End date: 2012-01-31
Institution: Yale University
Subfield: Cell Biology
Funded outputs count: 23
Funder award ID: R37AI023081
OpenAlex ID: G4937726233
Three Tapasin Docking Sites in TAP Cooperate To Facilitate Transporter Stabilization and Heterodimerization
2014 · Ralf M Leonhardt, Parwiz Abrahimi, et al. · The Journal of Immunology · 23
Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils
2013 · Ralf M. Leonhardt, Nathalie Vigneron, et al. · Molecular Biology of the Cell · 46
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A Switch in Pathogenic Mechanism in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis in IFN-γ–Inducible Lysosomal Thiol Reductase-Free Mice
2012 · Cheryl M Bergman, Cecilia B Marta, et al. · The Journal of Immunology · 26
TLR and Nucleotide-Binding Oligomerization Domain-like Receptor Signals Differentially Regulate Exogenous Antigen Presentation
2011 · Claudia S Wagner, Peter Cresswell · The Journal of Immunology · 42
Viperin: A Multifunctional, Interferon-Inducible Protein that Regulates Virus Replication
2011 · Jun-Young Seo, Rakina Yaneva, et al. · Cell Host & Microbe · 263
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Disulfide Reduction in the Endocytic Pathway: Immunological Functions of Gamma-Interferon-Inducible Lysosomal Thiol Reductase
2011 · Karen Taraszka Hastings, Peter Cresswell · Antioxidants and Redox Signaling · 104
Proprotein Convertases Process Pmel17 during Secretion
2011 · Ralf M. Leonhardt, Nathalie Vigneron, et al. · Journal of Biological Chemistry · 53
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GILT Accelerates Autoimmunity to the Melanoma Antigen Tyrosinase-Related Protein 1
2010 · Matthew P Rausch, Kari R Irvine, et al. · The Journal of Immunology · 56
Defective Cross-Presentation of Viral Antigens in GILT-Free Mice
2010 · Reshma Singh, Peter Cresswell · Science · 147
Endoplasmic Reticulum Export, Subcellular Distribution, and Fibril Formation by Pmel17 Require an Intact N-terminal Domain Junction
2010 · Ralf M. Leonhardt, Nathalie Vigneron, et al. · Journal of Biological Chemistry · 32
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Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation
2009 · Nathalie Vigneron, David R. Peaper, et al. · European Journal of Immunology · 27
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Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells
2009 · Alessandra Giodini, Christoph Rahner, et al. · Proceedings of the National Academy of Sciences · 74
GILT is a critical host factor for Listeria monocytogenes infection
2008 · Reshma Singh, Amanda Jamieson, et al. · Nature · 152
Target Peptide Sequence within Infectious Human Immunodeficiency Virus Type 1 Does Not Ensure Envelope-Specific T-Helper Cell Reactivation: Influences of Cysteine Protease and Gamma Interferon-Induced Thiol Reductase Activities
2008 · Robert Sealy, Wendy Chaka, et al. · Clinical and Vaccine Immunology · 30
Hsp90‐mediated cytosolic refolding of exogenous proteins internalized by dendritic cells
2007 · Alessandra Giodini, Peter Cresswell · The EMBO Journal · 91
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Innate Immune Recognition Triggers Secretion of Lysosomal Enzymes by Macrophages
2007 · Rebecca L. Lackman, Amanda M. Jamieson, et al. · Traffic · 75
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Exposure of the Promonocytic Cell Line THP-1 to Escherichia coli Induces IFN-γ-Inducible Lysosomal Thiol Reductase Expression by Inflammatory Cytokines
2006 · Rebecca L Lackman, Peter Cresswell · The Journal of Immunology · 62
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Enhanced and prolonged cross‐presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles
2005 · Hong Shen, Anne L. Ackerman, et al. · Immunology · 431
Role of the C-terminal propeptide in the activity and maturation of γ-interferon-inducible lysosomal thiol reductase (GILT)
2002 · Uyen T. Phan, Rebecca L. Lackman, et al. · Proceedings of the National Academy of Sciences · 33
Quality control of transmembrane domain assembly in the tetraspanin CD82
2001 · Kurt S. Cannon, Peter Cresswell · The EMBO Journal · 72
Enzymatic reduction of disulfide bonds in lysosomes: Characterization of a Gamma-interferon-inducible lysosomal thiol reductase (GILT)
2000 · Balasubramanian Arunachalam, Uyen T. Phan, et al. · Proceedings of the National Academy of Sciences · 443
Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome
1997 · Eric A. Hughes, Craig Hammond, et al. · Proceedings of the National Academy of Sciences · 302
HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules
1996 · Lisa K. Denzin, Craig Hammond, et al. · The Journal of Experimental Medicine · 205
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