Improved scalability, sensitivity, and interpretability of pathogen detection, including SARS-CoV-2, in wastewater using high-throughput, highly multiplexed digital array PCR technology
Description: PROJECT NARRATIVE The proposed research will enhance the usefulness of wastewater monitoring for pathogens to address public health responses to the COVID-19 pandemic as well as future pandemics. We will demonstrate highly multiplexed digital PCR assays on wastewater collected from multiple diverse geographical regions that will be comprehensive, rapid, low cost, and quantitative for monitoring the circulation of disease. Moreover, the assay system will be able to address novel pathogens by allowing rapid aggregation of genetic tests for these new targets.
Funder: National Institute on Drug Abuse
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2021-01-01
End date: 2024-05-31
Investigator: RACHEL TODD NOBLE (lead)
Institutions: University of North Carolina at Chapel Hill, UNIV OF NORTH CAROLINA CHAPEL HILL
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Funded outputs count: 6
Funder award ID: U01DA053899
OpenAlex ID: G493852273