Mechanism and Impact of an Interaction Between Keratin 19 and a Regulator of Gene Expression
Description: PROJECT NARRATIVE (Relevance to Public Health) High expressions of select keratins in tumors significantly correlate with poor patient prognoses. The proposed research examines a novel interaction of a keratin protein and a regulator of gene expression and its impact on promoting breast cancer metastasis. Our proposal has the potential to elucidate a key pathway in tumor metastasis and provide an underlying mechanism to design and develop more effective therapeutic strategies.
Funder: National Cancer Institute
Funding type: research
Funder scheme: R15
Start date: 2018-06-07
End date: 2022-05-31
Investigator: BYUNG MIN CHUNG
Institution: CATHOLIC UNIVERSITY OF AMERICA
Subfield: Cell Biology
Domain: Life Sciences
Funded outputs count: 10
Funder award ID: R15CA213071
OpenAlex ID: G4979808331