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A new model system to study brain aging and neurodegeneration

Description: PROJECT NARRATIVE Metabolic dysfunction is a common hallmark of aging and neurodegenerative disease. However, the reasons for age-related loss of energy homeostasis remain poorly understood due to limitations in systems to study the molecular mechanisms involved. This study will develop a new model system for studying how the neuroendocrine region of the brain ages.
Funding type: research
Funder scheme: R21
Start date: 2020-09-11
End date: 2023-08-31
Investigator: ASHLEY E WEBB
Institution: BROWN UNIVERSITY
Funded outputs count: 4
Funder award ID: R21AG070527
OpenAlex ID: G5070052257
2023 · Doudou Yu, Manlin Li, et al. · Cell Reports · 17
2022 · Kaitlyn H. Hajdarovic, Doudou Yu, et al. · Trends in Neurosciences · 35
2022 · Kaitlyn H. Hajdarovic, Doudou Yu, et al. · Nature Aging · 116
2014 · Sun, Ming Ming, et al. · International Journal of Technology Management
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