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Neovascular Regression for Oral Cancer Therapy

Funding type: research
Funder scheme: R01
Start date: 2002-04-01
End date: 2008-03-31
Investigator: JACQUES EDUARDO NOR
Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
Funded outputs count: 25
Funder award ID: R01DE014601
OpenAlex ID: G5217618015
RAIN-Droplet: a novel 3D in vitro angiogenesis model
2012 · Benjamin D Zeitlin, Zhihong Dong, et al. · Laboratory Investigation · 20
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Metronomic Dosing of BH3 Mimetic Small Molecule Yields Robust Antiangiogenic and Antitumor Effects
2011 · Atsushi Imai, Benjamin D. Zeitlin, et al. · Cancer Research · 17
Endothelial cell Bcl‐2 and lymph node metastasis in patients with oral squamous cell carcinoma
2011 · Sandra B. C. Tarquinio, Zhaocheng Zhang, et al. · Journal of Oral Pathology and Medicine · 7
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Endothelial Cell-Initiated Signaling Promotes the Survival and Self-Renewal of Cancer Stem Cells
2010 · Sudha Krishnamurthy, Zhihong Dong, et al. · Cancer Research · 265
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Efficient in vivo vascularization of tissue-engineering scaffolds
2010 · Anja Hegen, Anna Blois, et al. · Journal of Tissue Engineering and Regenerative Medicine · 57
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Metronomic Small Molecule Inhibitor of Bcl-2 (TW-37) Is Antiangiogenic and Potentiates the Antitumor Effect of Ionizing Radiation
2010 · Benjamin D. Zeitlin, Aaron C. Spalding, et al. · International Journal of Radiation Oncology*Biology*Physics · 19
Small-Molecule Inhibitors Reveal a New Function for Bcl-2 as a Proangiogenic Signaling Molecule
2010 · Benjamin D. Zeitlin, Jacques E. Nör · Current topics in microbiology and immunology · 11
VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
2009 · Z Zhang, K G Neiva, et al. · Cell Death and Differentiation · 197
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Cross talk Initiated by Endothelial Cells Enhances Migration and Inhibits Anoikis of Squamous Cell Carcinoma Cells through STAT3/Akt/ERK Signaling
2009 · Kathleen G. Neiva, Zhaocheng Zhang, et al. · Neoplasia · 149
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Gene expression analysis of immunostained endothelial cells isolated from formaldehyde‐fixated paraffin embedded tumors using laser capture microdissection—A technical report
2009 · Tomoatsu Kaneko, Takashi Okiji, et al. · Microscopy Research and Technique · 13
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Transcriptional targeting of tumor endothelial cells for gene therapy
2009 · Zhihong Dong, Jacques E. Nör · Advanced Drug Delivery Reviews · 33
TW-37, a small-molecule inhibitor of Bcl-2, mediates S-phase cell cycle arrest and suppresses head and neck tumor angiogenesis
2009 · Naoki Ashimori, Benjamin D. Zeitlin, et al. · Molecular Cancer Therapeutics · 47
Effect of PTK/ZK on the Angiogenic Switch in Head and Neck Tumors
2008 · M. Miyazawa, Z. Dong, et al. · Journal of Dental Research · 4
Expanding Circle of Inhibition: Small-Molecule Inhibitors of Bcl-2 as Anticancer Cell and Antiangiogenic Agents
2008 · Benjamin D. Zeitlin, Isaac J. Zeitlin, et al. · Journal of Clinical Oncology · 81
Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells
2008 · W Song, Z Dong, et al. · Cancer Gene Therapy · 18
Endothelial Cells Enhance Tumor Cell Invasion through a Crosstalk Mediated by CXC Chemokine Signaling
2008 · Kristy A. Warner, Marta Miyazawa, et al. · Neoplasia · 75
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Bcl-2 Orchestrates a Cross-talk between Endothelial and Tumor Cells that Promotes Tumor Growth
2007 · Tomoatsu Kaneko, Zhaocheng Zhang, et al. · Cancer Research · 107
Level of endothelial cell apoptosis required for a significant decrease in microvessel density
2007 · Zhihong Dong, Benjamin D. Zeitlin, et al. · Experimental Cell Research · 27
Quantification of human angiogenesis in immunodeficient mice using a photon counting-based method
2007 · Zhihong Dong, Kathleen G. Neiva, et al. · BioTechniques · 9
Unidirectional crosstalk between Bcl-xL and Bcl-2 enhances the angiogenic phenotype of endothelial cells
2007 · E Karl, Z Zhang, et al. · Cell Death and Differentiation · 52
Antiangiogenic Effect of TW37, a Small-Molecule Inhibitor of Bcl-2
2006 · Benjamin D. Zeitlin, Esther Joo, et al. · Cancer Research · 85
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Activation of iCaspase-9 in Neovessels Inhibits Oral Tumor Progression
2006 · M.S. Pinsky, W. Song, et al. · Journal of Dental Research · 9
Bcl-2 Acts in a Proangiogenic Signaling Pathway through Nuclear Factor-κB and CXC Chemokines
2005 · Elisabeta Karl, Kristy Warner, et al. · Cancer Research · 110
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Specific Occlusion of Murine and Human Tumor Vasculature by VCAM-1–Targeted Recombinant Fusion Proteins
2005 · Ariane Dienst, Andrea Grunow, et al. · JNCI Journal of the National Cancer Institute · 88
Antiangiogenic gene therapy: disruption of neovascular networks mediated by inducible caspase-9 delivered with a transcriptionally targeted adenoviral vector
2004 · W Song, Q Sun, et al. · Gene Therapy · 25
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