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Protons4Vision

Description: Uveal melanoma is the most common primary eye tumor. Proton beam therapy (PT) is capable of performing very local irradiation and is therefore one of the main eye-sparing treatments. In the PROTONS4vision project we will develop technologies that provide a more targeted and less invasive treatment. New high-resolution MRI technologies will be developed to locate the tumor in 3D. This will facilitate more precise treatment planning strategies that spare healthy tissues surrounding the tumor. MRI data and the new to be developed eye-tracking system will replace the use of tantalum clips, invasive markers that are currently used to locate the tumor in the eye. Upon project completion successful innovations will be implemented at HollandPTC, the first PT center in The Netherlands with a dedicated eye-beam. The developed technologies together serve one purpose: maximize intra-ocular tumor destruction, while minimizing vision loss and painful side effects, thereby optimizing the patient's quality-of-life.
Funding type: grant
Funder scheme: Samenwerkingsprogramma High Tech Systemen en Materialen (HTSM) 2015 STW
Start date: 2017-03-01
End date: 2021-11-14
Investigator: Andrew Webb
Institution: Leids Universitair Medisch Centrum
Funded outputs count: 13
Funder award ID: 14654
OpenAlex ID: G5308331981
2024 · Emmanuelle Fleury, Jean-Philippe Pignol, et al. · Physics and Imaging in Radiation Oncology · 7
2024 · Emmanuelle Fleury, Joël Herault, et al. · Physics in Medicine and Biology · 3
2022 · Myriam G. Jaarsma-Coes, Lisa Klaassen, et al. · Advances in Radiation Oncology · 14
2022 · Myriam G. Jaarsma-Coes, Teresa A. Ferreira, et al. · Ophthalmology Retina · 24
2021 · Teresa A. Ferreira, Myriam G. Jaarsma-Coes, et al. · Neuroradiology · 32
2021 · Myriam G. Jaarsma-Coes, Teresa A. Ferreira, et al. · Magnetic Resonance Materials in Physics Biology and Medicine · 9
2020 · Myriam G. Jaarsma-Coes, Marina Marinkovic, et al. · Physics and Imaging in Radiation Oncology · 7
2020 · Teresa A. Ferreira, Carolina F. Pinheiro, et al. · Cancers · 12
2019 · John M. Warman, Matthijs P. de Haas, et al. · Polymers · 13
2019 · Teresa A. Ferreira, Lorna Grech Fonk, et al. · Cancers · 74
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