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Advancing Vibrational Spectroscopy for Cellular and Sub Cellular Analysis

Amount: €1,034,000
Funding type: grant
Funder scheme: Principal Investigator Programme - nan
Start date: 2012-04-01
End date: 2018-07-31
Investigator: Hugh J. Byrne (lead)
Institutions: Technological University Dublin, Technological University Dublin (TU Dublin)
Subfield: Biophysics
Funded outputs count: 27
Funder award ID: 11/PI/1108
OpenAlex ID: G5407959577
Liposomal encapsulation of silver nanoparticles (AgNP) improved nanoparticle uptake and induced redox imbalance to activate caspase-dependent apoptosis
2019 · Azeez Yusuf, Alan Casey · APOPTOSIS · 35
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Surface modification of silver nanoparticle (AgNP) by liposomal encapsulation mitigates AgNP-induced inflammation
2019 · Azeez Yusuf, Alan Casey · Toxicology in Vitro · 31
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Evaluation of silver nanoparticle encapsulation in DPPC-based liposome by different methods for enhanced cytotoxicity
2019 · Azeez Yusuf, Alan Casey · International Journal of Polymeric Materials · 13
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Raman spectroscopy detects biochemical changes due to different cell culture environments in live cells in vitro
2018 · Mahmoud Gargotti, Esen Efeoglu, et al. · Analytical and Bioanalytical Chemistry · 26
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Advancing Raman microspectroscopy for cellular and subcellular analysis: towards in vitro high-content spectralomic analysis
2018 · Hugh J. Byrne, Franck Bonnier, et al. · Applied Optics · 34
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In vitro comparative cytotoxicity study of aminated polystyrene, zinc oxide and silver nanoparticles on a cervical cancer cell line
2018 · Akash Sharma, Brian Gorey, et al. · Drug and Chemical Toxicology · 31
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Toxicological assessment of nanomaterials: the role of in vitro Raman microspectroscopic analysis
2017 · Esen Efeoglu, Marcus A. Maher, et al. · Analytical and Bioanalytical Chemistry · 32
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Liposomal encapsulation of silver nanoparticles enhances cytotoxicity and causes induction of reactive oxygen species‐independent apoptosis
2017 · A. Yusuf, A. Brophy, et al. · Journal of Applied Toxicology · 40
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In vitro label‐free screening of chemotherapeutic drugs using Raman microspectroscopy: Towards a new paradigm of spectralomics
2017 · Zeineb Farhane, Haq Nawaz, et al. · Journal of Biophotonics · 32
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Comparative studies of cellular viability levels on 2D and 3D in vitro culture matrices
2017 · M. Gargotti, U. Lopez-Gonzalez, et al. · Cytotechnology · 48
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An in vitro study of the interaction of the chemotherapeutic drug Actinomycin D with lung cancer cell lines using Raman micro‐spectroscopy
2017 · Zeineb Farhane, Franck Bonnier, et al. · Journal of Biophotonics · 40
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Doxorubicin kinetics and effects on lung cancer cell lines using in vitro Raman micro‐spectroscopy: binding signatures, drug resistance and DNA repair
2017 · Zeineb Farhane, Franck Bonnier, et al. · Journal of Biophotonics · 43
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Industrial grade 2D molybdenum disulphide (MoS 2 ): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation
2017 · Caroline Moore, Dania Movia, et al. · 2D Materials · 69
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Label-free, high content screening using Raman microspectroscopy: the toxicological response of different cell lines to amine-modified polystyrene nanoparticles (PS-NH 2 )
2017 · Esen Efeoglu, Marcus A. Maher, et al. · The Analyst · 17
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Determination of spectral markers of cytotoxicity and genotoxicity using in vitro Raman microspectroscopy: cellular responses to polyamidoamine dendrimer exposure
2017 · Esen Efeoglu, Alan Casey, et al. · The Analyst · 14
Monitoring doxorubicin cellular uptake and trafficking using in vitro Raman microspectroscopy: short and long time exposure effects on lung cancer cell lines
2016 · Zeineb Farhane, Franck Bonnier, et al. · Analytical and Bioanalytical Chemistry · 77
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Gold nanostars for efficient in vitro and in vivo real-time SERS detection and drug delivery via plasmonic-tunable Raman/FTIR imaging
2016 · Furong Tian, João Conde, et al. · Biomaterials · 177
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Screening the low molecular weight fraction of human serum using ATR-IR spectroscopy
2016 · Franck Bonnier, Guillaume Brachet, et al. · Journal of Biophotonics · 71
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Spectroscopic studies of anthracyclines: Structural characterization and in vitro tracking
2016 · Ewelina Szafraniec, Katarzyna Majzner, et al. · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · 47
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Evaluation of cytotoxicity profile and intracellular localisation of doxorubicin-loaded chitosan nanoparticles
2016 · Gabriele Dadalt Souto, Zeineb Farhane, et al. · Analytical and Bioanalytical Chemistry · 31
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Differentiating responses of lung cancer cell lines to Doxorubicin exposure: in vitro Raman micro spectroscopy, oxidative stress and bcl‐2 protein expression
2016 · Zeineb Farhane, Franck Bonnier, et al. · Journal of Biophotonics · 61
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Chemotherapeutic efficiency of drugs in vitro: Comparison of doxorubicin exposure in 3D and 2D culture matrices
2016 · A. Casey, M. Gargotti, et al. · Toxicology in Vitro · 33
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In vitro monitoring of time and dose dependent cytotoxicity of aminated nanoparticles using Raman spectroscopy
2016 · Esen Efeoglu, Alan Casey, et al. · The Analyst · 40
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Investigating the Role of Shape on the Biological Impact of Gold Nanoparticles in Vitro
2015 · Furong Tian, Martin JD Clift, et al. · Nanomedicine · 40
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Determination of nanoparticle localisation within subcellular organelles in vitro using Raman spectroscopy
2015 · Esen Efeoglu, Mark Keating, et al. · Analytical Methods · 32
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