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Novel antibacterial agents resistant to inactivation by polyelectrolytes

Funding type: research
Funder scheme: R01
Start date: 2001-06-01
End date: 2012-06-30
Investigator: PAUL A JANMEY
Institution: UNIVERSITY OF PENNSYLVANIA
Funded outputs count: 44
Funder award ID: R01HL067286
OpenAlex ID: G5412377570
Cholesterol-Dependent Phase-Demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-Binding Cytoskeletal Protein Gelsolin
2016 · Yu-Hsiu Wang, Robert Bucki, et al. · Biochemistry · 18
Increased levels of sphingosine-1-phosphate in cerebrospinal fluid of patients diagnosed with tick-borne encephalitis
2014 · Alina Kułakowska, Fitzroy J Byfield, et al. · Journal of Neuroinflammation · 26
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阪南病院分教室 はじめの一歩 : 新しい分教室初年度の覚え書き
2013 · 将史 草川, 佳美 小濱, et al.
Antibacterial activity of the human host defence peptide LL-37 and selected synthetic cationic lipids against bacteria associated with oral and upper respiratory tract infections
2012 · K. Leszczynska, D. Namiot, et al. · Journal of Antimicrobial Chemotherapy · 84
Divalent Cation-Induced Cluster Formation by Polyphosphoinositides in Model Membranes
2012 · Yu-Hsiu Wang, Agnieszka Collins, et al. · Journal of the American Chemical Society · 131
Cathelicidin LL-37 Increases Lung Epithelial Cell Stiffness, Decreases Transepithelial Permeability, and Prevents Epithelial Invasion by Pseudomonas aeruginosa
2011 · Fitzroy J Byfield, Marek Kowalski, et al. · The Journal of Immunology · 54
Divalent Cation-Dependent Formation of Electrostatic PIP2 Clusters in Lipid Monolayers
2011 · Wouter G. Ellenbroek, Yu-Hsiu Wang, et al. · Biophysical Journal · 87
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Therapeutic potential of plasma gelsolin administration in a rat model of sepsis
2011 · Taylor S. Cohen, Robert Bucki, et al. · Cytokine · 37
Gelation of semiflexible polyelectrolytes by multivalent counterions
2011 · Elisabeth M. Huisman, Qi Wen, et al. · Soft Matter · 16
Depletion of Plasma Gelsolin in Patients with Tick-Borne Encephalitis and Lyme Neuroborreliosis
2011 · Alina Kułakowska, Joanna M. Zajkowska, et al. · Neurodegenerative Diseases · 18
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Cathelicidin LL-37 peptide regulates endothelial cell stiffness and endothelial barrier permeability
2010 · Fitzroy J. Byfield, Qi Wen, et al. · American Journal of Physiology-Cell Physiology · 49
Potential of ceragenin CSA-13 and its mixture with pluronic F-127 as treatment of topical bacterial infections
2010 · K. Leszczyńska, A. Namiot, et al. · Journal of Applied Microbiology · 64
Modulation of exogenous antibiotic activity by host cathelicidin LL‐37
2010 · KATARZYNA LESZCZYŃSKA, ANDRZEJ NAMIOT, et al. · Apmis · 20
Plasma gelsolin modulates cellular response to sphingosine 1-phosphate
2010 · Robert Bucki, Alina Kułakowska, et al. · American Journal of Physiology-Cell Physiology · 53
Combined Antibacterial and Anti-Inflammatory Activity of a Cationic Disubstituted Dexamethasone-Spermine Conjugate
2010 · Robert Bucki, Katarzyna Leszczyńska, et al. · Antimicrobial Agents and Chemotherapy · 24
Cholesterol-dependent phase separation in cell-derived giant plasma-membrane vesicles
2009 · Ilya Levental, Fitzroy J. Byfield, et al. · Biochemical Journal · 163
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Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice
2009 · Katarzyna Leszczyńska, Andrzej Namiot, et al. · BMC Microbiology · 62
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Calcium-Dependent Lateral Organization in Phosphatidylinositol 4,5-Bisphosphate (PIP2)- and Cholesterol-Containing Monolayers
2009 · Ilya Levental, David A. Christian, et al. · Biochemistry · 102
Combined Electrostatics and Hydrogen Bonding Determine Intermolecular Interactions Between Polyphosphoinositides
2008 · Ilya Levental, Andrejs Ce̅bers, et al. · Journal of the American Chemical Society · 57
Salivary mucins inhibit antibacterial activity of the cathelicidin-derived LL-37 peptide but not the cationic steroid CSA-13
2008 · R. Bucki, D. B. Namiot, et al. · Journal of Antimicrobial Chemotherapy · 70
Resistance of the antibacterial agent ceragenin CSA-13 to inactivation by DNA or F-actin and its activity in cystic fibrosis sputum
2007 · Robert Bucki, Audra Goach Sostarecz, et al. · Journal of Antimicrobial Chemotherapy · 73
Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum
2007 · R. Bucki, F. J. Byfield, et al. · European Respiratory Journal · 107
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Interaction of the Gelsolin-Derived Antibacterial PBP 10 Peptide with Lipid Bilayers and Cell Membranes
2006 · Robert Bucki, Paul A. Janmey · Antimicrobial Agents and Chemotherapy · 56
Temperature Effects on Threshold Counterion Concentration to Induce Aggregation of fd Virus
2006 · Qi Wen, Jay X. Tang · Physical Review Letters · 24
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Low Flagellar Motor Torque and High Swimming Efficiency of Caulobacter crescentus Swarmer Cells
2006 · Guanglai Li, Jay X. Tang · Biophysical Journal · 82
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