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AI080749

Funded outputs count: 23
Funder award ID: AI080749
OpenAlex ID: G545428362
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 · Philip J. Kranzusch, Amy S.Y. Lee, et al. · Cell · 127
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Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes
2014 · Jeannette L. Tenthorey, Eric M. Kofoed, et al. · Molecular Cell · 196
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Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor
2013 · Joseph Chavarría-Smith, Russell E. Vance · PLoS Pathogens · 239
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IL-1α Signaling Initiates the Inflammatory Response to Virulent Legionella pneumophila In Vivo
2013 · Kevin C Barry, Mary F Fontana, et al. · The Journal of Immunology · 129
The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
2013 · Elie J. Diner, Dara L. Burdette, et al. · Cell Reports · 761
STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during Chlamydia trachomatis Infection
2013 · Jeffrey R. Barker, Benjamin J. Koestler, et al. · mBio · 235
Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
2013 · Joseph Conlon, Dara L Burdette, et al. · The Journal of Immunology · 435
Caspase-11 Protects Against Bacteria That Escape the Vacuole
2013 · Youssef Aachoui, Irina A. Leaf, et al. · Science · 543
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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
2012 · Jakob von Moltke, Norver J. Trinidad, et al. · Nature · 437
Activation of Host Mitogen-Activated Protein Kinases by Secreted Legionella pneumophila Effectors That Inhibit Host Protein Translation
2012 · Mary F. Fontana, Sunny Shin, et al. · Infection and Immunity · 67
Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota
2012 · Janelle S Ayres, Norver J Trinidad, et al. · Nature Medicine · 212
NAIPs: Building an innate immune barrier against bacterial pathogens
2012 · Eric M. Kofoed, Russell E. Vance · BioEssays · 51
STING is a direct innate immune sensor of cyclic di-GMP
2011 · Dara L. Burdette, Kathryn M. Monroe, et al. · Nature · 1,562
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
2011 · Eric M. Kofoed, Russell E. Vance · Nature · 891
Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila
2011 · Mary F. Fontana, Simran Banga, et al. · PLoS Pathogens · 226
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Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome
2011 · Karla L. Lightfield, Jenny Persson, et al. · Infection and Immunity · 135
TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
2010 · John-Demian Sauer, Katia Sotelo-Troha, et al. · Infection and Immunity · 539
H‐NOX regulation of c‐di‐GMP metabolism and biofilm formation in Legionella pneumophila
2010 · Hans K. Carlson, Russell E. Vance, et al. · Molecular Microbiology · 126
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Induction of type I interferons by bacteria
2010 · Kathryn M. Monroe, Sarah M. McWhirter, et al. · Cellular Microbiology · 144
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Inflammasome Activation: How Macrophages Watch What They Eat
2010 · Russell E. Vance · Cell Host & Microbe · 7
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Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila
2009 · Kathryn M. Monroe, Sarah M. McWhirter, et al. · PLoS Pathogens · 191
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A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
2009 · Sarah M. McWhirter, Roman Barbalat, et al. · The Journal of Experimental Medicine · 296
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Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System
2009 · Russell E. Vance, Ralph R. Isberg, et al. · Cell Host & Microbe · 517
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