Homologous Recombination in Genome Stability and Tumor Suppression
Description: Relevance to Public Health Chromosome aberrations are a hallmark of human cancer, and can be useful indicators of patient prognosis. In this proposal we will investigate the origins of cancer-related chromosome aberrations and the mechanisms by which they occur. Identifying these mechanisms will be key to designing better cancer diagnostic tests; refining prognostic markers; and developing new cancer therapies based on tumor-specific properties.
Funder: National Cancer Institute
Funding type: research
Funder scheme: R01
Start date: 2009-06-08
End date: 2013-05-31
Investigator: KEVIN D MILLS
Institution: JACKSON LABORATORY
Funded outputs count: 4
Funder award ID: R01CA138646
OpenAlex ID: G5728199057