Towards a Complete Description of the Circuitry Underlying Sharp Wave-Mediated Memory Replay
Description: We propose to make the first attempt to fully understand a cognitively important event, called memory replay, in terms of the detailed properties of the brain cells involved. We will use cutting-edge large- scale recording technologies to study and manipulate identified cell types in behaving animals, and we will construct the first full-scale computational of model of the brain area that produces the memory replay in which every cell is explicitly simulated. These powerful new approaches are likely to yield major insights into the principles by which the interactions of neurons gives rise to cognitive function, with important implications for memory disorders.
Funding type: cooperative_agreement
Funder scheme: U19
Start date: 2017-09-25
End date: 2023-06-30
Investigator: GYORGY BUZSAKI
Institution: STANFORD UNIVERSITY
Funded outputs count: 99
Funder award ID: U19NS104590
OpenAlex ID: G577703167