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FTO泛素化介导MFG-E8m6A甲基化动态修饰调控COPD肺泡上皮细胞凋亡的机制研究

Amount: ¥540,000
Funding type: grant
Funder scheme: 面上项目
Start date: 2020-01-01
End date: 2024-12-31
Investigator: 燕 陈 (lead)
Institutions: Central South University, 中南大学
Funded outputs count: 40
Funder award ID: 82070049
OpenAlex ID: G577903576
The impact of hyperglycemia on prognosis in chronic obstructive pulmonary disease patients with coronary heart disease: A five-year prospective study
2025 · Zhongshang Dai, Chenjie He, et al. · PLoS ONE · 2
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Clinical characteristics of patients with positive fungal pathogens during acute exacerbation of chronic obstructive pulmonary disease: A retrospective study
2025 · Lijuan Luo, Lijun Liu, et al. · Chinese Medical Journal - Pulmonary and Critical Care Medicine · 8
Current status of pharmacists in community pharmacies in China in the health management of chronic respiratory diseases
2025 · Jiankang Wu, Hongtao Niu, et al. · BMC Public Health · 5
Lung organoids in COPD: recent advances and future prospects
2025 · Yajie Huo, Shengyang He, et al. · Respiratory Research · 19
LncRNA MALAT1 regulates cigarette smoke induced airway inflammation by modulating miR-30a-5p/JNK signaling pathway
2024 · Xiangming Liu, Yiming Ma, et al. · International Immunopharmacology · 9
Unraveling the Connection: Extracellular Vesicles and Non-Small Cell Lung Cancer
2024 · Jiankang Wu, Yan Chen · International Journal of Nanomedicine · 8
Analysis of clinical characteristics, prognosis and influencing factors in patients with bronchiectasis-chronic obstructive pulmonary disease overlap syndrome: A prospective study for more than five years
2024 · Zhongshang Dai, Yanjun Zhong, et al. · Journal of Global Health · 8
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MiRNA-210 is involved in cigarette smoke extract-induced apoptosis of MLE-12 via the Shh signaling pathway
2024 · Zhongshang Dai*+, Zijie Zhan*+, et al. · Tobacco Induced Diseases · 2
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CAPN5 attenuates cigarette smoke extract-induced apoptosis and inflammation in BEAS-2B cells
2024 · Herui Li, Yiming Ma, et al. · Tobacco Induced Diseases · 1
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Suboptimal peak inspiratory flow rate: a noticeable risk factor for inhaler concordance in patients with chronic airway diseases
2024 · Weiwei Meng, Ruoyan Xiong, et al. · BMJ Open Respiratory Research · 10
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Early smoking lead to worse prognosis of COPD patients: a real world study
2024 · Jiankang Wu, Weiwei Meng, et al. · Respiratory Research · 28
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TET2 stabilized by deubiquitinase USP21 ameliorates cigarette smoke-induced apoptosis in airway epithelial cells
2024 · Lijuan Luo, Zihang Zeng, et al. · iScience · 7
PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways
2024 · Xue He<sup>+</sup>, Yanan Cui<sup>+</sup>, et al. · Tobacco Induced Diseases · 3
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Machine learning-assisted construction of COPD self-evaluation questionnaire (COPD-EQ): a national multicentre study in China
2024 · Yiming Ma, Zijie Zhan, et al. · Journal of Global Health · 5
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Reliability and validity test and application of the Chinese version of the Feeling of Satisfaction with Inhaler.
2023 · Weiwei Meng, Zhiqi Zhao, et al. · PubMed Central
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Nemonoxacin achieved a better symptomatic improvement and a prolonged interval to next exacerbation than moxifloxacin for outpatients with acute exacerbations of chronic obstructive pulmonary disease
2023 · Weiwei Meng, Huihui Zeng, et al. · Scientific Reports · 3
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DNA dioxygenases TET2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell
2023 · Zihang Zeng, Tiao Li, et al. · Redox Biology · 69
CSE reduces OTUD4 triggering lung epithelial cell apoptosis via PAI-1 degradation
2023 · Lijuan Luo, Tiao Li, et al. · Cell Death and Disease · 15
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Blood eosinophils in chronic obstructive pulmonary disease: A potential biomarker
2023 · Yanan Cui, Yan Chen · Journal of Translational Internal Medicine · 8
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Does the 2017 global initiative for chronic obstructive lung disease revision really improve the assessment of Chinese chronic obstructive pulmonary disease patients? A multicenter prospective study for more than 5 years
2023 · Yanan Cui, Yiming Ma, et al. · Chinese Medical Journal · 2
Extracellular vesicles and COPD: foe or friend?
2023 · Jiankang Wu, Yiming Ma, et al. · Journal of Nanobiotechnology · 36
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MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells
2023 · Yanan Cui, Lijuan Luo, et al. · Cell Death and Disease · 42
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Taxifolin ameliorates cigarette smoke-induced chronic obstructive pulmonary disease via inhibiting inflammation and apoptosis
2022 · Xiangming Liu, Yiming Ma, et al. · International Immunopharmacology · 24
GERD-related chronic cough: Possible mechanism, diagnosis and treatment
2022 · Jiankang Wu, Yiming Ma, et al. · Frontiers in Physiology · 51
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Extracellular Vesicle Derived From Mesenchymal Stem Cells Have Bidirectional Effects on the Development of Lung Cancer
2022 · Jiayu Wang, Yiming Ma, et al. · Frontiers in Oncology · 9