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MC_PC_17228
Funder:
Medical Research Council
Funded outputs count:
4,470
Funder award ID:
MC_PC_17228
OpenAlex ID:
G5850737185
Polygenic score for sleep duration in relation to the risk of Alzheimer’s disease: results from the UK biobank
2026
·
Angel TY Wong
, Sarah Floud
, et al.
·
Frontiers in Dementia
PDF
Cardiovascular measures from abdominal MRI provide insights into abdominal vessel genetic architecture
2026
·
Nicolas Basty
, Elena P. Sorokin
, et al.
·
Communications Medicine
·
3
PDF
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
2025
·
Charlotte Fraza
, Mariam Zabihi
, et al.
·
Human Brain Mapping
·
6
PDF
Genetic liability to major psychiatric disorders contributes to multi-faceted quality of life outcomes in children and adults
2025
·
Yingjie Shi
, Nina Roth Mota
, et al.
·
Translational Psychiatry
·
6
PDF
A mathematical model that predicts human biological age from physiological traits identifies environmental and genetic factors that influence aging
2025
·
Sergiy Libert
, Alex Chekholko
, et al.
·
eLife
·
6
Parsing Clinical and Neurobiological Sources of Heterogeneity in Depression
2025
·
Kayla Hannon
, Ty Easley
, et al.
·
Biological Psychiatry
·
11
PDF
The Trait Coding Rule in Phenotype Space
2025
·
Jianguo Wang
, Xionglei He
·
Phenomics
·
1
PDF
White Matter Microstructural Alterations in Type 2 Diabetes: A Combined UK Biobank Study of Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging
2025
·
Abdulmajeed Alotaibi
, Mostafa Alqarras
, et al.
·
Medicina
·
12
Balancing the risk of major bleeding against vascular disease risk in people without atherosclerotic disease
2025
·
Imen Hammami
, Marion Mafham
, et al.
·
Heart
·
1
Secure and federated genome-wide association studies for biobank-scale datasets
2025
·
Hyunghoon Cho
, David Froelicher
, et al.
·
Nature Genetics
·
35
Genetic association studies using disease liabilities from deep neural networks
2025
·
Lu Yang
, Marie C. Sadler
, et al.
·
The American Journal of Human Genetics
·
8
Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy
2025
·
Rafik Tadros
, Sean L. Zheng
, et al.
·
Nature Genetics
·
70
PDF
Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries
2024
·
Bryan R. Gorman
, Georgios Voloudakis
, et al.
·
Nature Genetics
·
57
PDF
Sex-Specific Association Between Genetic Risk of Psychiatric Disorders and Cardiovascular Diseases
2024
·
Jiayue-Clara Jiang
, Kritika Singh
, et al.
·
Circulation Genomic and Precision Medicine
·
18
Hemochromatosis neural archetype reveals iron disruption in motor circuits
2024
·
Robert Loughnan
, Jonathan Ahern
, et al.
·
Science Advances
·
6
Genome-wide association neural networks identify genes linked to family history of Alzheimer’s disease
2024
·
Upamanyu Ghose
, William Sproviero
, et al.
·
Briefings in Bioinformatics
·
14
PDF
Accuracy of healthcare systems data for identifying cardiovascular outcomes after stroke due to intracerebral haemorrhage in the United Kingdom
2024
·
Alice Hosking
, Jacqueline Stephen
, et al.
·
Trials
·
2
PDF
The potential for improving cardio-renal outcomes in chronic kidney disease with the aldosterone synthase inhibitor vicadrostat (BI 690517): a rationale for the EASi-KIDNEY trial
2024
·
Parminder K Judge
, Katherine R Tuttle
, et al.
·
Nephrology Dialysis Transplantation
·
77
Striatal dopamine gene network moderates the effect of early adversity on the risk for adult psychiatric and cardiometabolic comorbidity
2024
·
Barbara Barth
, Danusa Mar Arcego
, et al.
·
Scientific Reports
·
12
PDF
A comprehensive study of genetic regulation and disease associations of plasma circulatory microRNAs using population-level data
2024
·
Rima Mustafa
, Michelle M. J. Mens
, et al.
·
Genome biology
·
15
PDF
Quantifying constraint in the human mitochondrial genome
2024
·
Nicole J. Lake
, Kaiyue Ma
, et al.
·
Nature
·
60
PDF
Optimizing and benchmarking polygenic risk scores with GWAS summary statistics
2024
·
Zijie Zhao
, Tim Gruenloh
, et al.
·
Genome biology
·
27
PDF
Regionally enriched rare deleterious exonic variants in the UK and Ireland
2024
·
Mihail Halachev
, Viktoria-Eleni Gountouna
, et al.
·
Nature Communications
·
7
PDF
FUSE: Improving the estimation and imputation of variant impacts in functional screening
2024
·
Tian Yu
, James D. Fife
, et al.
·
Cell Genomics
·
8
Blood Pressure, eGFR, and Kidney Mortality in Mexico: A Prospective Study of 150,000 Adults
2024
·
Doreen Zhu
, Pablo Antonio Kuri-Morales
, et al.
·
Journal of the American Society of Nephrology
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