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Pharmacology of Receptor/effector Systems

Funding type: program
Funder scheme: P01
Start date: 1985-04-01
End date: 1995-03-31
Investigator: PERRY B MOLINOFF
Institution: UNIVERSITY OF PENNSYLVANIA
Funded outputs count: 68
Funder award ID: 5p01gm034781-07
OpenAlex ID: G620656343
Interaction of Somatostatin Receptors with G Proteins and Cellular Effector Systems
2007 · Terry Reisine, Donna Woulfe, et al. · Novartis Foundation symposium · 20
Effect of Repeated Administration of Clenbuterol on the Regulation of β‐Adrenoceptors in the Central Nervous System of the Rat
2007 · Alan Frazer, Gregory Ordway, et al. · Novartis Foundation symposium · 12
Cyclobutane Quisqualic Acid Analogues as Selective mGluR5a Metabotropic Glutamic Acid Receptor Ligands
1999 · Louis Littman, Christopher Tokar, et al. · Journal of Medicinal Chemistry · 15
Basal ganglia and movement disorders: an update
1996 · Marie-Françoise Chesselet, Jill M Delfs · Trends in Neurosciences · 385
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Multiplicity of glutamate receptor subunits in single striatal neurons: an RNA amplification study.
1996 · M B Ghasemzadeh, S Sharma, et al. · Molecular Pharmacology · 71
Pharmacological and immunological characterization of N-methyl-D-aspartate receptors in human NT2-N neurons.
1996 · M Munir, L Lu, et al. · Journal of Pharmacology and Experimental Therapeutics · 17
Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells
1995 · M Munir, L Lu, et al. · Journal of Neuroscience · 60
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Effects of quisqualic acid analogs on metabotropic glutamate receptors coupled to phosphoinositide hydrolysis in rat hippocampus
1995 · L. Littman, L.A. Chase, et al. · Neuropharmacology · 24
Intrastriatal injections of the succinate dehydrogenase inhibitor, malonate, cause a rise in extracellular amino acids that is blocked by MK-801
1995 · Conrad A. Messam, James G. Greene, et al. · Brain Research · 30
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Type 4a metabotropic glutamate receptor: identification of new potent agonists and differentiation from the L-(+)-2-amino-4-phosphonobutanoic acid-sensitive receptor in the lateral perforant pathway in rats.
1995 · P A Johansen, L A Chase, et al. · Molecular Pharmacology · 66
Anatomical localization of SKF‐38393‐induced behaviors in rats using the irreversible monoamine receptor antagonist EEDQ
1995 · Janet L. Neisewander, Alvin Ong, et al. · Synapse · 16
Expression of mRNAs Encoding Subunits of the NMDA Receptor in Developing Rat Brain
1995 · Jie Zhong, David P. Carrozza, et al. · Journal of Neurochemistry · 251
Somatostatin receptor activation of cellular effector systems
1995 · Susan F. Law, Donna Woulfe, et al. · Cellular Signalling · 51
The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons
1994 · R Maki, MB Robinson, et al. · Journal of Neuroscience · 98
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Modulation of the N-methyl- d -aspartate receptor by polyamines: molecular pharmacology and mechanisms of action
1994 · Keith Williams · Biochemical Society Transactions · 19
The Effects of l ‐Glutamate and trans‐(±)‐1‐Amino‐1,3‐Cyclopentanedicarboxylate on Phosphoinositide Hydrolysis Can Be Pharmacologically Differentiated
1994 · Louis Littman, Michael B. Robinson · Journal of Neurochemistry · 18
Serotonergic properties of cocaine: Effects on a 5-HT2 receptor-mediated behavior and on extracellular concentrations of serotonin and dopamine
1994 · W.D. Essman, A. Singh, et al. · Pharmacology Biochemistry and Behavior · 45
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Subunit-specific potentiation of recombinant N-methyl-D-aspartate receptors by histamine.
1994 · K Williams · Molecular Pharmacology · 76
Dopaminergic Stimulation of Subthalamic Nucleus Elicits Oral Dyskinesia in Rats
1994 · Tom J. Parry, Kim Eberle-Wang, et al. · Experimental Neurology · 52
Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors.
1994 · K Williams · Molecular Pharmacology · 78
Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits.
1994 · K Williams, A M Zappia, et al. · Molecular Pharmacology · 226
Expression of mRNAs encoding subunits of the N-methyl-D-aspartate receptor in cultured cortical neurons.
1994 · J Zhong, S L Russell, et al. · Molecular Pharmacology · 136
Regional Profile of Developmental Changes in the Sensitivity of theN‐Methyl‐D‐Aspartate Receptor to Polyamines
1994 · Swaminathan Subramaniam, Paul McGonigle · Journal of Neurochemistry · 16
Failure to myristoylate the alpha subunit of Gz is correlated with an inhibition of palmitoylation and membrane attachment, but has no affect on phosphorylation by protein kinase C.
1994 · H. Hallak, L.F. Brass, et al. · Journal of Biological Chemistry · 55
Covalent binding of arachidonate to G protein alpha subunits of human platelets.
1994 · H. Hallak, L. Muszbek, et al. · Journal of Biological Chemistry · 116
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