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R01-NS082311

Funded outputs count: 98
Funder award ID: R01-NS082311
OpenAlex ID: G645032831
The discrete charm of oncolytic viruses: Toward the finish line
2025 · Pedro R. Lowenstein, Maria Luisa Varela, et al. · Cancer Cell · 25
Genetically Engineered and Implantable Mouse Brain Tumor Models: Characterization by Immunohistochemistry and Flow Cytometry
2025 · Apoorva Mirji, Gurveer Singh, et al. · Current Protocols · 2
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Epigenetic reprogramming in pediatric gliomas: from molecular mechanisms to therapeutic implications
2024 · Santiago Haase, Stephen Carney, et al. · Trends in cancer · 13
Three recent breakthroughs in CAR T cells for the treatment of glioblastoma: Is it the light at the end of the tunnel?
2024 · Pedro R. Lowenstein, Maria Luisa Varela, et al. · Molecular Therapy · 1
Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways
2024 · Syed M. Faisal, Jarred E. Clewner, et al. · Advanced Science · 18
Modeling Glioma Oncostreams In Vitro: Spatiotemporal Dynamics of their Formation, Stability, and Disassembly
2023 · Syed M. Faisal, Jarred E Clewner, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial
2023 · Yoshie Umemura, Daniel Orringer, et al. · The Lancet Oncology · 64
Combined cytotoxic and immune-stimulatory gene therapy using Ad-TK and Ad-Flt3L: Translational developments from rodents to glioma patients
2023 · Syed M. Faisal, Maria G. Castro, et al. · Molecular Therapy · 25
H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Diffuse Hemispheric Gliomas
2023 · Maria B. Garcia-Fabiani, Santiago Haase, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 9
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Sabotaging the protein factory to overcome glioma stem cell resistance
2023 · Santiago Haase, Pedro R Lowenstein, et al. · Neuro-Oncology · 1
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Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis
2023 · Andrea Comba, Maria Luisa Varela, et al. · STAR Protocols · 5
Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance
2023 · Stephen V. Carney, Kaushik Banerjee, et al. · Clinical Cancer Research · 13
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Impact of epigenetic reprogramming on antitumor immune responses in glioma
2023 · Brandon L. McClellan, Santiago Haase, et al. · Journal of Clinical Investigation · 65
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Gene Therapy for High Grade Glioma: The Clinical Experience
2022 · Maria Luisa Varela, Andrea Comba, et al. · Expert Opinion on Biological Therapy · 33
The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications
2022 · Syed M. Faisal, Andrea Comba, et al. · Frontiers in Oncology · 56
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H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models
2022 · Santiago Haase, Kaushik Banerjee, et al. · Journal of Clinical Investigation · 84
Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment
2022 · Andrea Franson, Brandon L. McClellan, et al. · Frontiers in Medicine · 31
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Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
2022 · Andrea Comba, Syed M. Faisal, et al. · Nature Communications · 109
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Systemic Delivery of an Adjuvant CXCR4–CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy
2022 · Mahmoud S. Alghamri, Kaushik Banerjee, et al. · ACS Nano · 148
Murine brain tumor microenvironment immunophenotyping using mass cytometry
2022 · Brandon L. McClellan, Mahmoud S. Alghamri, et al. · STAR Protocols · 2
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ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization
2022 · Tingting Qin, Brendan Mullan, et al. · Cell Reports · 77
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G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy
2021 · Mahmoud S. Alghamri, Brandon L. McClellan, et al. · Science Advances · 93
Systemic delivery of a CXCR4-CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy
2021 · Mahmoud S Alghamri, Kaushik Banerjee, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications
2021 · Andrea Comba, Syed M. Faisal, et al. · Frontiers in Oncology · 72
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Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments
2021 · Mahmoud S. Alghamri, Brandon L. McClellan, et al. · Frontiers in Pharmacology · 90
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