NAD+/NADH ratio, protein acetylation and mitochondrial function
Description: NARRATIVE The proposed study will determine the role of NAD+/NADH ratioin regulating protein acetylation and mitochondrial function in the heart. By manipulating NAD+ level in the failing hearts, we seek to identify and target novel NAD+/NADH sensitive mechanisms for heart failure therapy.
Funder: National Institutes of Health
Amount: $773,900
Funding type: research
Funder scheme: R01
Start date: 2011-08-15
End date: 2023-02-28
Investigator: RONG TIAN
Institution: UNIVERSITY OF WASHINGTON
Funded outputs count: 10
Funder award ID: 5r01hl110349-08
OpenAlex ID: G6787456622