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Progression of Uveitis and CD8 uveitogenic T cells

Funding type: research
Funder scheme: R01
Start date: 2007-02-01
End date: 2013-02-28
Investigator: DEMING SUN
Institution: DOHENY EYE INSTITUTE
Funded outputs count: 32
Funder award ID: R01EY017373
OpenAlex ID: G696705707
The role of Th17-associated cytokines in the pathogenesis of experimental autoimmune uveitis (EAU)
2015 · Deming Sun, Dongchun Liang, et al. · Cytokine · 36
Retinoic Acid Inhibits CD25 + Dendritic Cell Expansion and γδ T-Cell Activation in Experimental Autoimmune Uveitis
2013 · Dongchun Liang, Aijun Zuo, et al. · Investigative Ophthalmology & Visual Science · 28
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Role of CD25+ Dendritic Cells in the Generation of Th17 Autoreactive T Cells in Autoimmune Experimental Uveitis
2012 · Dongchun Liang, Aijun Zuo, et al. · The Journal of Immunology · 38
In vivo priming of IL-17+ uveitogenic T cells is enhanced by Toll ligand receptor (TLR)2 and TLR4 agonists via γδ T cell activation
2012 · Aijun Zuo, Dongchun Liang, et al. · Molecular Immunology · 19
Characterization of Autoreactive and Bystander IL-17 + T Cells Induced in Immunized C57BL/6 Mice
2012 · Hong Nian, Dongchun Liang, et al. · Investigative Ophthalmology & Visual Science · 28
IL-22–Induced Regulatory CD11b+ APCs Suppress Experimental Autoimmune Uveitis
2011 · Yan Ke, Deming Sun, et al. · The Journal of Immunology · 55
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A Distinct Role of CD4+ Th17- and Th17-Stimulated CD8+ CTL in the Pathogenesis of Type 1 Diabetes and Experimental Autoimmune Encephalomyelitis
2011 · Manjunatha Ankathatti Munegowda, Yulin Deng, et al. · Journal of Clinical Immunology · 30
Activated γδ T Cells Promote the Activation of Uveitogenic T Cells and Exacerbate EAU Development
2011 · Hong Nian, Hui Shao, et al. · Investigative Ophthalmology & Visual Science · 58
Anti-CD3 antibody ameliorates experimental autoimmune uveitis by inducing both IL-10 and TGF-β dependent regulatory T cells
2011 · Yan Ke, Guomin Jiang, et al. · Clinical Immunology · 21
PD-L1hi retinal pigment epithelium (RPE) cells elicited by inflammatory cytokines induce regulatory activity in uveitogenic T cells
2010 · Yan Ke, Deming Sun, et al. · Journal of Leukocyte Biology · 39
Regulatory Effect of γδ T Cells on IL-17 + Uveitogenic T Cells
2010 · Hong Nian, Hui Shao, et al. · Investigative Ophthalmology & Visual Science · 39
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Analysis of γδ T Cell Functions in the Mouse
2010 · Willi K Born, Zhinan Yin, et al. · The Journal of Immunology · 63
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Regulation of Interphotoreceptor Retinoid-Binding Protein (IRBP)-Specific Th1 and Th17 Cells in Anterior Chamber-Associated Immune Deviation (ACAID)
2009 · Yan Cui, Hui Shao, et al. · Investigative Ophthalmology & Visual Science · 5
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Regulatory Role of TLR Ligands on the Activation of Autoreactive T Cells by Retinal Astrocytes
2009 · Guomin Jiang, Yan Ke, et al. · Investigative Ophthalmology & Visual Science · 38
Retinal astrocytes respond to IL-17 differently than retinal pigment epithelial cells
2009 · Yan Ke, Guomin Jiang, et al. · Journal of Leukocyte Biology · 26
Major Role of γδ T Cells in the Generation of IL-17+ Uveitogenic T Cells
2009 · Yan Cui, Hui Shao, et al. · The Journal of Immunology · 112
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Anti-Inflammatory Role of IL-17 in Experimental Autoimmune Uveitis
2009 · Yan Ke, Ke Liu, et al. · The Journal of Immunology · 101
Mouse γδ T cells are capable of expressing MHC class II molecules, and of functioning as antigen-presenting cells
2008 · Lan Cheng, Yan Cui, et al. · Journal of Neuroimmunology · 95
Ocular Regulatory T Cells Distinguish Monophasic from Recurrent Autoimmune Uveitis
2008 · Yan Ke, Guomin Jiang, et al. · Investigative Ophthalmology & Visual Science · 37
Reactivation of Uveitogenic T Cells by Retinal Astrocytes Derived from Experimental Autoimmune Uveitis-Prone B10RIII Mice
2008 · Guomin Jiang, Yan Ke, et al. · Investigative Ophthalmology & Visual Science · 37
Sequence 168 to 177 of interphotoreceptor retinoid-binding protein (IRBP) is an antigenic epitope for autoreactive CD8 T cells in the B10RIII mouse
2007 · Lei Song, Junyi Le, et al. · Journal of Neuroimmunology · 13
Novel Exosome-Targeted CD4+ T Cell Vaccine Counteracting CD4+25+ Regulatory T Cell-Mediated Immune Suppression and Stimulating Efficient Central Memory CD8+ CTL Responses
2007 · Siguo Hao, Yongqing Liu, et al. · The Journal of Immunology · 70
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Characterization of IL-17 + Interphotoreceptor Retinoid-Binding Protein-Specific T Cells in Experimental Autoimmune Uveitis
2007 · Yong Peng, Gencheng Han, et al. · Investigative Ophthalmology & Visual Science · 119
Suppression of Established Experimental Autoimmune Uveitis by Anti-LFA-1α Ab
2007 · Yan Ke, Deming Sun, et al. · Investigative Ophthalmology & Visual Science · 16
Minimally Activated CD8 Autoreactive T Cells Specific for IRBP Express a High Level of Foxp3 and Are Functionally Suppressive
2007 · Yong Peng, Hui Shao, et al. · Investigative Ophthalmology & Visual Science · 30
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