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22932
Funder:
Cancer Research UK
Funded outputs count:
41
Funder award ID:
22932
OpenAlex ID:
G7212898136
Association of DCIS size and margin status with risk of developing breast cancer post-treatment: multinational, pooled cohort study
2023
·
Renée S J M Schmitz
, Alexandra W van den Belt-Dusebout
, et al.
·
BMJ
·
37
PDF
Diagnosis of Ovarian Carcinoma Homologous Recombination DNA Repair Deficiency From Targeted Gene Capture Oncology Assays
2023
·
Niklas Krumm
, Nithisha S. Khasnavis
, et al.
·
JCO Precision Oncology
·
6
PDF
A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
2023
·
Stefan J. Hutten
, Roebi de Bruijn
, et al.
·
Cancer Cell
·
34
PDF
A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer
2022
·
Marine Inglebert
, Martina Dettwiler
, et al.
·
Scientific Reports
·
41
PDF
Learning to distinguish progressive and non-progressive ductal carcinoma in situ
2022
·
Anna K. Casasent
, Mathilde M. Almekinders
, et al.
·
Nature reviews. Cancer
·
50
Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
2022
·
Erika Durinikova
, Nicole M. Reilly
, et al.
·
Clinical Cancer Research
·
60
PDF
Two Secreted Proteoglycans, Activators of Urothelial Cell–Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression
2020
·
Vasiliki Papadaki
, Ken Asada
, et al.
·
Cancers
·
31
ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer
2020
·
R.E. Miller
, A. Leary
, et al.
·
Annals of Oncology
·
483
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
2020
·
Matthew H. Bailey
, William U. Meyerson
, et al.
·
Nature Communications
·
52
PDF
Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
2020
·
Dominik Glodzik
, Ana Bosch
, et al.
·
Nature Communications
·
127
PDF
Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer
2020
·
Neha Chopra
, Holly Tovey
, et al.
·
Nature Communications
·
259
PDF
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
2020
·
Ilias Georgakopoulos-Soares
, Gene Koh
, et al.
·
Nature Communications
·
28
PDF
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
2020
·
Oliver Thompson
, Ferdinand von Meyenn
, et al.
·
Nature Communications
·
140
PDF
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies
2020
·
Andrea Degasperi
, Tauanne Dias Amarante
, et al.
·
Nature Cancer
·
299
Mutational signatures: experimental design and analytical framework
2020
·
Gene Koh
, Xueqing Zou
, et al.
·
Genome biology
·
39
PDF
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
2020
·
Wei Jiao
, Gurnit Atwal
, et al.
·
Nature Communications
·
217
PDF
Pan-cancer analysis of whole genomes
2020
·
Lauri A. Aaltonen
, Federico Abascal
, et al.
·
Nature
·
3,055
PDF
Holistic cancer genome profiling for every patient
2020
·
Serena Nik-Zainal
, Yasin Memari
, et al.
·
Swiss Medical Weekly
·
6
Cellular survival over genomic perfection
2019
·
Serena Nik-Zainal
, Benjamin A. Hall
·
Science
·
31
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome
2019
·
Helen R. Davies
, Kirsty Hodgson
, et al.
·
Nature Communications
·
35
PDF
Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment decision in end-stage disease
2019
·
Sophie Momen
, Hiva Fassihi
, et al.
·
Molecular Case Studies
·
48
PDF
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies
2019
·
Lindsay Angus
, Marcel Smid
, et al.
·
Nature Genetics
·
309
Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study
2019
·
Johan Staaf
, Dominik Glodzik
, et al.
·
Nature Medicine
·
305
Ductal carcinoma in situ: to treat or not to treat, that is the question
2019
·
on behalf of the PRECISION team
, Maartje van Seijen
, et al.
·
British Journal of Cancer
·
320
PDF
A practical guide for mutational signature analysis in hematological malignancies
2019
·
Francesco Maura
, Andrea Degasperi
, et al.
·
Nature Communications
·
183
PDF
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