Award

Role of a novel angiogenic factor, YKL-40, in breast cancer progression

Funder: National Cancer Institute

Funding type: research

Funder scheme: R01

Start date: 2008-05-01

End date: 2014-02-28

Investigator: RONG SHAO

Institution: UNIVERSITY OF MASSACHUSETTS AMHERST

Funded outputs count: 14

Funder award ID: R01CA120659

OpenAlex ID: G765192142

Anti-YKL-40 antibody and ionizing irradiation synergistically inhibit tumor vascularization and malignancy in glioblastoma

2013 · R. Shao, R. Francescone, et al. · Carcinogenesis · 68

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Tumor-derived mural-like cells coordinate with endothelial cells: role of YKL-40 in mural cell-mediated angiogenesis

2013 · R Francescone, N Ngernyuang, et al. · Oncogene · 38

YKL-40 acts as an angiogenic factor to promote tumor angiogenesis

2013 · Rong Shao · Frontiers in Physiology · 133

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Transdifferentiation of Glioblastoma Stem-Like Cells into Mural Cells Drives Vasculogenic Mimicry in Glioblastomas

2012 · Steve Scully, Ralph Francescone, et al. · Journal of Neuroscience · 165

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Glioblastoma-derived Tumor Cells Induce Vasculogenic Mimicry through Flk-1 Protein Activation

2012 · Ralph Francescone, Steve Scully, et al. · Journal of Biological Chemistry · 143

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Diego de Ordás: el hombre que domó un volcán

2012 · José Javier Esparza · Epoca

Inhibitory Activity of YKL-40 in Mammary Epithelial Cell Differentiation and Polarization Induced by Lactogenic Hormones: A Role in Mammary Tissue Involution

2011 · Steve Scully, Wei Yan, et al. · PLoS ONE · 44

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Breast cancer expression of YKL-40 correlates with tumour grade, poor differentiation, and other cancer markers

2011 · R Shao, Q J Cao, et al. · British Journal of Cancer · 86

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A Matrigel-Based Tube Formation Assay to Assess the Vasculogenic Activity of Tumor Cells

2011 · Ralph A. Francescone III, Michael Faibish, et al. · Journal of Visualized Experiments · 127

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Role of YKL-40 in the Angiogenesis, Radioresistance, and Progression of Glioblastoma

2011 · Ralph A. Francescone, Steve Scully, et al. · Journal of Biological Chemistry · 256

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The novel lupus antigen related protein acheron enhances the development of human breast cancer

2011 · Rong Shao, Steve J. Scully, et al. · International Journal of Cancer · 29

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A YKL-40–Neutralizing Antibody Blocks Tumor Angiogenesis and Progression: A Potential Therapeutic Agent in Cancers

2011 · Michael Faibish, Ralph Francescone, et al. · Molecular Cancer Therapeutics · 180

GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition

2010 · Wei Yan, Qing Jackie Cao, et al. · Journal of Biological Chemistry · 225

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YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

2009 · R Shao, K Hamel, et al. · Oncogene · 286