Vaccine Design to Concentrate Protective Antibodies at the Mucosal Border
Description: An effective HIV-1 vaccine is urgently needed, particularly to prevent transmission to women who increasingly bear the brunt of newly acquired infections. The proposed research is based on a protective live attenuated vaccine, and seeks to reproduce these protective effects without the associated safety issues, with novel immunogens and strategies that focus the immune response on intercepting infection at the portal of entry in its early stages of infection when virus is most vulnerable.
Funding type: research
Funder scheme: R01
Start date: 2012-07-25
End date: 2017-06-30
Investigator: ASHLEY T. HAASE
Institution: UNIVERSITY OF MINNESOTA
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Funded outputs count: 6
Funder award ID: R01AI102625
OpenAlex ID: G7828172198