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R35 CA197623

Funded outputs count: 49
Funder award ID: R35 CA197623
OpenAlex ID: G784047723
Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response
2026 · Zheqi Li, Amatullah Tawawalla, et al. · Nature Communications
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HER2 Heterogeneous Breast Cancer Models Reveal Novel Therapeutic Targets and Subclonal Dynamics during Evolution to Resistance to HER2-Targeted Therapies
2026 · Marie-Anne Goyette, Christopher Graser, et al. · Cancer Discovery · 1
KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage
2025 · Zheqi Li, Guillermo Peluffo, et al. · Nature Genetics · 11
Epigenetic drivers of metalloproteinases and metastasis
2025 · Marco Seehawer, Kornelia Polyak · Trends in Cell Biology · 7
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ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer
2024 · Benedetto DiCiaccio, Marco Seehawer, et al. · Cell Reports · 12
TBCRC 039: a phase II study of preoperative ruxolitinib with or without paclitaxel for triple-negative inflammatory breast cancer
2024 · Winer, Eric P., Lange, Paulina, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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Midkine as a driver of age-related changes and increase in mammary tumorigenesis
2024 · Pengze Yan, Ernesto Rojas Jimenez, et al. · Cancer Cell · 47
Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3
2024 · Marco Seehawer, Zheqi Li, et al. · Nature Cell Biology · 48
Cancer–stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies
2024 · Marie-Anne Goyette, Laura E. Stevens, et al. · Proceedings of the National Academy of Sciences · 33
HER2 heterogeneity and treatment response–associated profiles in HER2-positive breast cancer in the NCT02326974 clinical trial
2024 · Zheqi Li, Otto Metzger Filho, et al. · Journal of Clinical Investigation · 33
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TBCRC 039: a phase II study of preoperative ruxolitinib with or without paclitaxel for triple-negative inflammatory breast cancer
2024 · Filipa Lynce, Laura E. Stevens, et al. · Breast Cancer Research · 23
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Heterogeneity and transcriptional drivers of triple-negative breast cancer
2023 · Bojana Jovanović, Daniel Temko, et al. · Cell Reports · 34
Peripheral blood TCR clonotype diversity as an age-associated marker of breast cancer progression
2023 · Jun Nishida, Simona Cristea, et al. · Proceedings of the National Academy of Sciences · 11
HATS off to KAT6A/B inhibitors: A new way to target estrogen-receptor-positive breast cancer
2023 · Rinath Jeselsohn, Kornelia Polyak · Cell chemical biology · 9
Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer
2023 · Maša Alečković, Zheqi Li, et al. · Molecular Cancer Therapeutics · 19
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A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
2023 · Connor Stashko, Mary-Kate Hayward, et al. · Nature Communications · 62
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Clinical and translational relevance of intratumor heterogeneity
2023 · Marie-Anne Goyette, Marla Lipsyc-Sharf, et al. · Trends in cancer · 53
Challenges and opportunities for modeling aging and cancer
2023 · Olga Anczuków, Susie Airhart, et al. · Cancer Cell · 25
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Breast cancer prevention by short-term inhibition of TGFβ signaling
2022 · Maša Alečković, Simona Cristea, et al. · Nature Communications · 14
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JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
2022 · Laura E. Stevens, Guillermo Peluffo, et al. · Cancer Research · 103
Untangling the web of intratumour heterogeneity
2022 · Zheqi Li, Marco Seehawer, et al. · Nature Cell Biology · 82
Bacterial Darth Vader: May the force be with you
2022 · Kornelia Polyak · Cancer Cell · 2
Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer
2022 · Carlos R. Gil Del Alcazar, Anne Trinh, et al. · Cancer Immunology Research · 30
A Darwinian perspective on tumor immune evasion
2021 · Julieann Puleo, Kornelia Polyak · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 23
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The MCF10 Model of Breast Tumor Progression
2021 · Julieann Puleo, Kornelia Polyak · Cancer Research · 49
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