Targeting Caspase 8 in T-Cell Homeostasis and Disease
Description: Chronic infectious diseases such as HIV, hepatitis B and tuberculosis impose a massive global health burden and new treatments are desperately needed. This proposal investigates a new approach to improve immune responses and clear chronic infections. Our multidisciplinary team will define the molecular and cellular biology underlying this approach and translate our findings by re-purposing a drug already approved for other indications in humans.
Amount: A$1,216,000
Funding type: research
Funder scheme: Project Grants - Standard Project Grant
Start date: 2018-01-01
End date: 2021-12-31
Investigator: Daniel Gray (lead)
Institutions: Walter and Eliza Hall Institute of Medical Research, Walter and Eliza Hall Institute
Funded outputs count: 11
Funder award ID: 1145888
OpenAlex ID: G786333239