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P01 CA013106
Funder:
National Cancer Institute
Funded outputs count:
425
Funder award ID:
P01 CA013106
OpenAlex ID:
G789504050
Vulnerability of triple negative breast cancer to daraxonrasib pan-RAS(on) inhibition
2026
·
Michael P. East
, J. Felix Olivares-Quintero
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
A Newly Characterized, Two BRCT Domain-Containing Isoform of PAX-Interacting Protein (PTIP) Generated via Frame Shift and Alternative Pre-mRNA Splicing
2025
·
Ching-Jung Huang
, Chuan Li
, et al.
·
Journal of Cellular Signaling
·
1
PDF
KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2
2025
·
Patrick J. Cunniff
, Nicole Sivetz
, et al.
·
Nature Communications
·
4
PDF
Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3
2025
·
Aktan Alpsoy
, Jonathan J. Ipsaro
, et al.
·
Cell Reports
·
1
PDF
Longitudinal tracking of MALAT1 level over a breast cancer patient’s course of treatment and disease progression
2025
·
Disha Aggarwal
, Tse-Luen Wee
, et al.
·
Molecular Therapy Oncology
·
1
Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors
2025
·
Michael F. Ciccone
, Dhivyaa Anandan
, et al.
·
Nature Communications
·
1
SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence
2025
·
Kaloyan M. Tsanov
, Francisco M. Barriga
, et al.
·
Nature Cancer
·
10
LINC01235 Is an Upstream Regulator of the NFIB Gene and the Notch Pathway in Triple-Negative Breast Cancer
2025
·
Wenbo Xu
, Sonam Bhatia
, et al.
·
Molecular Cancer Research
·
2
PDF
Microbial metabolite ammonia disrupts TGF-β signaling to promote colon cancer
2025
·
Krishanu Bhowmick
, Xiaochun Yang
, et al.
·
Journal of Biological Chemistry
·
5
New insights into biomarkers and risk stratification to predict hepatocellular cancer
2025
·
Katrina Li
, Brandon Mathew
, et al.
·
Molecular Medicine
·
16
PDF
PKM splice-switching ASOs induce upregulation of dual-specificity phosphatases and dephosphorylation of ERK1/2 in hepatocellular carcinoma
2025
·
Dillon M. Voss
, Alexander J. Kral
, et al.
·
Journal of Biological Chemistry
·
8
PDF
Voltage-gated sodium channels in excitable cells as drug targets
2025
·
Matthew Alsaloum
, Sulayman D. Dib-Hajj
, et al.
·
Nature Reviews Drug Discovery
·
61
Human Pancreatic Cancer Single-Cell Atlas Reveals Association of CXCL10+ Fibroblasts and Basal Subtype Tumor Cells
2024
·
Ian M. Loveless
, Samantha B. Kemp
, et al.
·
Clinical Cancer Research
·
57
PTPN23-dependent ESCRT machinery functions as a cell death checkpoint
2024
·
Dongyan Song
, Yuxin Cen
, et al.
·
Nature Communications
·
7
PDF
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms
2024
·
Siyu Sun
, Eunae You
, et al.
·
Immunity
·
34
Aldehydes alter TGF-β signaling and induce obesity and cancer
2024
·
Xiaochun Yang
, Krishanu Bhowmick
, et al.
·
Cell Reports
·
17
The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade
2024
·
Yijian Qiu
, Olivia T. Stamatatos
, et al.
·
Nature Metabolism
·
29
PDF
MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer
2024
·
Olaf Klingbeil
, Damianos Skopelitis
, et al.
·
Cancer Discovery
·
32
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma
2024
·
Diogo Maia-Silva
, Patrick J. Cunniff
, et al.
·
Nature Genetics
·
17
PDF
Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids
2024
·
Ledong Wan
, Ledong Wan
, et al.
·
Nucleic Acid Therapeutics
·
17
PDF
Opportunities and challenges for innovative and equitable healthcare
2024
·
David J. Ecker
, Clarice D. Aiello
, et al.
·
Nature Reviews Drug Discovery
·
8
Therapeutic index of targeting select chromatin complexes in human cancer patients
2024
·
Yuan Gao
, Christopher R Vakoc
·
Current Opinion in Genetics & Development
·
1
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment
2024
·
Xue-Yan He
, Yuan Gao
, et al.
·
Cancer Cell
·
291
IκBζ is a dual-use coactivator of NF-κB and POU transcription factors
2024
·
Aktan Alpsoy
, Xiaoli S. Wu
, et al.
·
Molecular Cell
·
14
A mucus production programme promotes classical pancreatic ductal adenocarcinoma
2024
·
Claudia Tonelli
, Georgi N Yordanov
, et al.
·
Gut
·
33
PDF
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