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The Role of PGRN Growth Factor in Osteoarthritis. - Renewal - 1

Description: Narrative The proposed studies will present a novel chondroprotective growth factor, its derivatives and provide a better understanding of growth factor and cytokine in chondrocytes and in the pathogenesis of OA. Identification of novel molecules and their derivatives relevant to chondrocytes is the basis for developing and optimizing the application of the novel therapeutic targets in cartilage disorders, including OA.
Funding type: research
Funder scheme: R01
Start date: 2011-09-01
End date: 2023-06-30
Investigator: CHUANJU LIU
Institution: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
Funded outputs count: 86
Funder award ID: R01AR061484
OpenAlex ID: G6726288445
2025 · Emily Qian, Ryan S MacLeod, et al. · Journal of Leukocyte Biology · 1
2025 · Renpeng Zhou, Wei Hu, et al. · Trends in Pharmacological Sciences · 16
2025 · Chuan-ju Liu · Science · 8
2025 · Sadaf Hasan, Nabil Ghani, et al. · Genes & Diseases · 12
2024 · Yu-jia-nan Chen, Rong-chen Shi, et al. · Signal Transduction and Targeted Therapy · 38
2024 · Renpeng Zhou, Weirong Hu, et al. · Bone Research · 22
2024 · Renpeng Zhou, Wenyu Fu, et al. · Nature Reviews Rheumatology · 69
2024 · Xiaohong Kong, Chuan‐Ju Liu · Clinical and Translational Medicine · 7
2024 · Wenyu Fu, Dmytro Vasylyev, et al. · Nature · 123
2023 · Guiwu Huang, Jinlong Jian, et al. · Cytokine & Growth Factor Reviews · 20
2023 · Yuzhao Liu, Xiangli Zhao, et al. · BioScience Trends · 3
2023 · Meng Chen, Wenyu Fu, et al. · Cytokine & Growth Factor Reviews · 152
2022 · Xiangli Zhao, Yi Lin, et al. · Proceedings of the National Academy of Sciences · 20
2022 · Xiangli Zhao, Sadaf Hasan, et al. · International Journal of Molecular Sciences · 4
2021 · Kai-di Wang, Xiang Ding, et al. · Annals of the Rheumatic Diseases · 63
2021 · Xiangli Zhao, Ronghan Liu, et al. · International Journal of Molecular Sciences · 16
2021 · Xiangli Zhao, Rossella Liberti, et al. · Journal of Molecular Medicine · 20
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