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Regulation of adipocyte differentiation and metabolism

Funding type: research
Funder scheme: R01
Start date: 1996-07-25
End date: 2012-06-30
Investigator: ORMOND A MACDOUGALD
Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
Funded outputs count: 45
Funder award ID: R01DK051563
OpenAlex ID: G7991074845
Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition
2012 · Hiroyuki Mori, Tyler C. Prestwich, et al. · Journal of Clinical Investigation · 162
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Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
2012 · Alfiya Akhmetshina, Katrin Palumbo, et al. · Nature Communications · 864
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Adipose tissue stem cells: the great WAT hope
2012 · William P. Cawthorn, Erica L. Scheller, et al. · Trends in Endocrinology and Metabolism · 99
Adipose tissue stem cells meet preadipocyte commitment: going back to the future
2011 · William P. Cawthorn, Erica L. Scheller, et al. · Journal of Lipid Research · 466
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Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism
2011 · William P. Cawthorn, Adam J. Bree, et al. · Bone · 418
The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression
2011 · Xin Wen, William P. Cawthorn, et al. · Biomaterials · 44
Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?
2011 · Jun Wei, Denisa Melichian, et al. · Arthritis & Rheumatism · 226
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Regulation of Lipid Homeostasis by the Bifunctional SREBF2-miR33a Locus
2011 · Guido T. Bommer, Ormond A. MacDougald · Cell Metabolism · 94
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Multiple Roles for the Non-Coding RNA SRA in Regulation of Adipogenesis and Insulin Sensitivity
2010 · Bin Xu, Isabelle Gerin, et al. · PLoS ONE · 204
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Visualization by BiFC of different C/EBPβ dimers and their interaction with HP1α reveals a differential subnuclear distribution of complexes in living cells
2010 · Sebastián Susperreguy, Luciana P. Prendes, et al. · Experimental Cell Research · 17
Expression of miR-33 from an SREBP2 Intron Inhibits Cholesterol Export and Fatty Acid Oxidation*
2010 · Isabelle Gerin, Laure-Alix Clerbaux, et al. · Journal of Biological Chemistry · 384
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Reversibly sealed multilayer microfluidic device for integrated cell perfusion and on-line chemical analysis of cultured adipocyte secretions
2010 · Anna M. Clark, Kyle M. Sousa, et al. · Analytical and Bioanalytical Chemistry · 28
Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis
2010 · Isabelle Gerin, Guido T. Bommer, et al. · American Journal of Physiology-Endocrinology and Metabolism · 256
The many facets of PPARγ: novel insights for the skeleton
2010 · Masanobu Kawai, Kyle M. Sousa, et al. · American Journal of Physiology-Endocrinology and Metabolism · 62
Critical roles for the TSC-mTOR pathway in β-cell function
2009 · Hiroyuki Mori, Ken Inoki, et al. · American Journal of Physiology-Endocrinology and Metabolism · 104
Critical Role for Hypothalamic mTOR Activity in Energy Balance
2009 · Hiroyuki Mori, Ken Inoki, et al. · Cell Metabolism · 189
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On the Role of FOX Transcription Factors in Adipocyte Differentiation and Insulin-stimulated Glucose Uptake
2009 · Isabelle Gerin, Guido T. Bommer, et al. · Journal of Biological Chemistry · 65
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Continuous-Flow Enzyme Assay on a Microfluidic Chip for Monitoring Glycerol Secretion from Cultured Adipocytes
2009 · Anna M. Clark, Kyle M. Sousa, et al. · Analytical Chemistry · 75
Regulation of Cyclin D1 and Wnt10b Gene Expression by cAMP-responsive Element-binding Protein during Early Adipogenesis Involves Differential Promoter Methylation
2008 · Keith E. Fox, Lillester A. Colton, et al. · Journal of Biological Chemistry · 58
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Hyperphagia and Obesity in Female Mice Lacking Tissue Inhibitor of Metalloproteinase-1
2008 · Isabelle Gerin, Gwendolyn W. Louis, et al. · Endocrinology · 24
Wnt/β-catenin signaling in adipogenesis and metabolism
2007 · Tyler C Prestwich, Ormond A MacDougald · Current Opinion in Cell Biology · 364
Wnt10b Increases Postnatal Bone Formation by Enhancing Osteoblast Differentiation
2007 · Christina N Bennett, Hongjiao Ouyang, et al. · Journal of Bone and Mineral Research · 285
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Wnt10b Inhibits Obesity in ob/ob and Agouti Mice
2007 · Wendy S. Wright, Kenneth A. Longo, et al. · Diabetes · 172
Wnt Signaling Inhibits Adipogenesis through β-Catenin-dependent and -independent Mechanisms
2005 · Jennifer A. Kennell, Ormond A. MacDougald · Journal of Biological Chemistry · 250
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LXRβ Is Required for Adipocyte Growth, Glucose Homeostasis, and β Cell Function
2005 · Isabelle Gerin, Vernon W. Dolinsky, et al. · Journal of Biological Chemistry · 174
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