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Transcription Coupled Repair of Eukaryotic Cells

Funding type: research
Funder scheme: R01
Start date: 1985-07-01
End date: 2005-02-28
Investigator: STEVEN A LEADON
Institution: UNIVERSITY OF NORTH CAROLINA CHAPEL HILL
Funded outputs count: 23
Funder award ID: R01CA040453
OpenAlex ID: G7992601132
The Ataxia telangiectasia Gene Product Is Required for Oxidative Stress-induced G1 and G2Checkpoint Function in Human Fibroblasts
2001 · Rodney E. Shackelford, Cynthia L. Innes, et al. · Journal of Biological Chemistry · 127
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Measurement of Oxidative DNA Damage and Repair in Specific DNA Sequences
2000 · Anna V. Avrutskaya, Steven A. Leadon · Methods · 6
Measuring DNA Damage Using Capillary Electrophoresis with Laser-Induced Fluorescence Detection
2000 · James Z. Xing, Jane Lee, et al. · Methods · 20
RETRACTED: Transcription-Coupled Repair of 8-oxoGuanine
2000 · Florence Le Page, Ely E. Kwoh, et al. · Cell · 280
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Transcription-coupled Repair: A Multifunctional Signaling Pathway
2000 · S.A. LEADON · Cold Spring Harbor Symposia on Quantitative Biology · 9
Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light
1999 · Karen M Meyer, Suzanne M Hess, et al. · Oncogene · 38
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RETRACTED: Growth Retardation, DNA Repair Defects, and Lack of Spermatogenesis in BRCA1-Deficient Mice
1999 · Victoria L. Cressman, Dana C. Backlund, et al. · Molecular and Cellular Biology · 108
BRCA1 Required for Transcription-Coupled Repair of Oxidative DNA Damage
1998 · Lori C. Gowen, Anna V. Avrutskaya, et al. · Science · 491
Inducible Repair of Thymine Glycol Detected by an Ultrasensitive Assay for DNA Damage
1998 · X. Chris Le, James Z. Xing, et al. · Science · 205
RETRACTED: Requirement for DNA mismatch repair proteins in the transcription-coupled repair of thymine glycols in Saccharomyces cerevisiae
1998 · Steven A. Leadon, Anna V. Avrutskaya · Mutation Research/DNA Repair · 42
Differential involvement of the human mismatch repair proteins, hMLH1 and hMSH2, in transcription-coupled repair.
1997 · S A Leadon, A V Avrutskaya · PubMed · 78
RETRACTED: A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function
1997 · Thierry Nouspikel, Philippe Lalle, et al. · Proceedings of the National Academy of Sciences · 170
Defective Transcription-Coupled Repair of Oxidative Base Damage in Cockayne Syndrome Patients from XP Group G
1997 · Priscilla K. Cooper, Thierry Nouspikel, et al. · Science · 307
RETRACTED: The yeast RAD2, but not RAD1, gene is involved in the transcription-coupled repair of thymine glycols
1995 · Steven A. Leadon, Susan L. Barbee, et al. · Mutation Research/DNA Repair · 32
Defective Repair of Ionizing Radiation Damage in Cockayne's Syndrome and Xeroderma Pigmentosum Group Ga
1994 · PRISCILLA K. COOPER, STEVEN A. LEADON · Annals of the New York Academy of Sciences · 10
Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome.
1993 · S A Leadon, P K Cooper · Proceedings of the National Academy of Sciences · 214
Strand-selective repair of DNA damage in the yeast GAL7 gene requires RNA polymerase II
1992 · S.A. Leadon, D.A. Lawrence · Journal of Biological Chemistry · 131
Relationship of resistance to oxygen free radicals to CuZn‐superoxide dismutase activity in transgenic, transfected, and trisomic cells
1992 · Ting‐Ting Huang, Elaine J. Carlson, et al. · The FASEB Journal · 53
Preferential repair of DNA damage on the transcribed strand of the human metallothionein genes requires RNA polymerase II
1991 · Steven A. Leadon, David A. Lawrence · Mutation Research/DNA Repair · 109
Production and Repair of DNA Damage in Mammalian Cells
1990 · Steven A. Leadon · Health Physics · 20
Differential Repair of DNA Damage in the Human Metallothionein Gene Family
1988 · S A Leadon, M M Snowden · Molecular and Cellular Biology · 71
Production of oxidative DNA damage during the metabolic activation of benzo[a]pyrene in human mammary epithelial cells correlates with cell killing.
1988 · S A Leadon, M R Stampfer, et al. · Proceedings of the National Academy of Sciences · 73
Differential repair of DNA damage in specific nucleotide sequences in monkey cells
1986 · Steven A. Leadon · Nucleic Acids Research · 30
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