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The significance of adult neurogenesis

Description: To understand the significance of adult neurogenesis, we genetically ablated newly born neurons in the adult mouse brain. Mutant mice showed defects in predator odor avoidance. Furthermore, mutant males displayed deficits in male-male aggression and sexual behaviors toward females, while mutant females displayed deficits in fertility and nurturing. These results suggest that adult neurogenesis plays an essential role in predator avoidance and gender-specific responses that are olfactory-dependent and innately programmed.

Funder: Japan Society for the Promotion of Science

Amount: ¥47,320,000

Funding type: research

Funder scheme: Grant-in-Aid for Scientific Research (A)

Investigator: Maryoichiro KAGEYA

Institution: Kyoto University

Topic: Neurogenesis and neuroplasticity mechanisms

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

Funded outputs count: 21

Funder award ID: 21240028

OpenAlex ID: G8090795355