Holographic imprinting of novelty detection in mice
Description: PROJECT NARRATIVE Patients with schizophrenia show deficits of elementary sensory processing, affecting their ability of automatic focusing and interact with the changing environment. We will use state of the art methods to record the activity of hundreds of neurons from the mouse cortex, and simultaneously use holographic optogenetics to manipulate the ongoing activity and control behavior output. Finally we will use a holographic imprinting of stimulus evoked activity in a mouse model of schizophrenia to improve the neuronal population activity and attempt to rescue the disease phenotype
Funding type: fellowship
Funder scheme: F31
Start date: 2019-09-16
End date: 2022-09-15
Investigator: YURIY SHYMKIV
Institution: COLUMBIA UNIV NEW YORK MORNINGSIDE
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Funded outputs count: 5
Funder award ID: F31MH122137
OpenAlex ID: G8317808608