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Kinetic Properties of Selectins

Funding type: research
Funder scheme: R21
Start date: 2000-03-15
End date: 2001-02-28
Investigator: CHENG ZHU
Institution: GEORGIA INSTITUTE OF TECHNOLOGY
Funded outputs count: 36
Funder award ID: R21AI044902
OpenAlex ID: G838954571
Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release, and coagulation
2018 · Aiming Pang, Yujie Cui, et al. · Blood · 86
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Receptor-mediated cell mechanosensing
2017 · Yunfeng Chen, Lining Ju, et al. · Molecular Biology of the Cell · 229
Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases
2017 · Hiroshi Nishi, Kazuhiro Furuhashi, et al. · Journal of Clinical Investigation · 69
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The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy
2017 · Guangheng Zhu, Qing Zhang, et al. · Blood · 76
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Regulation of actin catch-slip bonds with a RhoA-formin module
2016 · Cho-yin Lee, Jizhong Lou, et al. · Scientific Reports · 16
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Flow-Enhanced Stability of Rolling Adhesion through E-Selectin
2016 · Quhuan Li, Annica Wayman, et al. · Biophysical Journal · 27
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Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell
2015 · Yunfeng Chen, Baoyu Liu, et al. · Journal of Visualized Experiments · 50
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Pre-TCR ligand binding impacts thymocyte development before αβTCR expression
2015 · Robert J. Mallis, Ke Bai, et al. · Proceedings of the National Academy of Sciences · 75
A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force
2015 · Florencia Rosetti, Yunfeng Chen, et al. · Cell Reports · 72
Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis
2013 · Young I. Choi, Jonathan S. Duke-Cohan, et al. · Proceedings of the National Academy of Sciences · 76
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Mechanochemitry: A Molecular Biomechanics View of Mechanosensing
2013 · Cheng Zhu · Annals of Biomedical Engineering · 30
Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds
2013 · Cho-yin Lee, Jizhong Lou, et al. · Proceedings of the National Academy of Sciences · 78
Cyclic Mechanical Reinforcement of Integrin–Ligand Interactions
2013 · Fang Kong, Zhenhai Li, et al. · Molecular Cell · 154
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Structural Basis and Kinetics of Force-Induced Conformational Changes of an αA Domain-Containing Integrin
2011 · Xue Xiang, Cho-yin Lee, et al. · PLoS ONE · 21
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Molecular Dynamics Simulations of Forced Unbending of Integrin αVβ3
2011 · Wei Chen, Jizhong Lou, et al. · PLoS Computational Biology · 74
Rolling Cell Adhesion
2010 · Rodger P. McEver, Cheng Zhu · Annual Review of Cell and Developmental Biology · 376
Forcing Switch from Short- to Intermediate- and Long-lived States of the αA Domain Generates LFA-1/ICAM-1 Catch Bonds
2010 · Wei Chen, Jizhong Lou, et al. · Journal of Biological Chemistry · 183
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Triphasic Force Dependence of E-Selectin/Ligand Dissociation Governs Cell Rolling under Flow
2010 · Annica M. Wayman, Wei Chen, et al. · Biophysical Journal · 54
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Demonstration of catch bonds between an integrin and its ligand
2009 · Fang Kong, Andrés J. García, et al. · The Journal of Cell Biology · 693
Measuring Receptor–Ligand Binding Kinetics on Cell Surfaces: From Adhesion Frequency to Thermal Fluctuation Methods
2008 · Wei Chen, Veronika I. Zarnitsyna, et al. · Cellular and Molecular Bioengineering · 86
Binary Time Series Modeling With Application to Adhesion Frequency Experiments
2008 · Ying Hung, Veronika Zarnitsyna, et al. · Journal of the American Statistical Association · 16
Mechanisms for Flow-Enhanced Cell Adhesion
2008 · Cheng Zhu, Tadayuki Yago, et al. · Annals of Biomedical Engineering · 108
Two Stage Cadherin Kinetics Require Multiple Extracellular Domains but Not the Cytoplasmic Region
2007 · Yuan-Hung Chien, Ning Jiang, et al. · Journal of Biological Chemistry · 58
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Memory in receptor–ligand-mediated cell adhesion
2007 · Veronika I. Zarnitsyna, Jun Huang, et al. · Proceedings of the National Academy of Sciences · 57
Monitoring Receptor-Ligand Interactions between Surfaces by Thermal Fluctuations
2007 · Wei Chen, Evan A. Evans, et al. · Biophysical Journal · 121
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