Get started
Award

JP16H06444

Funded outputs count: 17
Funder award ID: JP16H06444
OpenAlex ID: G8497079110
Discovery, biochemical characterization, and bioengineering of cyanobactin prenyltransferases
2022 · Yuchen Zhang, Yuki Goto, et al. · Trends in Biochemical Sciences · 44
Post-translational backbone-acyl shift yields natural product-like peptides bearing hydroxyhydrocarbon units
2022 · Tomohiro Kuroda, Yichao Huang, et al. · Nature Chemistry · 14
De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors
2022 · Alexander A. Vinogradov, Yue Zhang, et al. · Journal of the American Chemical Society · 67
Solid-Phase-Based Synthesis of Lactazole-Like Thiopeptides
2022 · Yue Zhang, Alexander A. Vinogradov, et al. · Organic Letters · 15
LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
2022 · Yuchen Zhang, Keisuke Hamada, et al. · Nature Catalysis · 44
PDF
Accurate Models of Substrate Preferences of Post-Translational Modification Enzymes from a Combination of mRNA Display and Deep Learning
2022 · Alexander A. Vinogradov, Jun Shi Chang, et al. · ACS Central Science · 43
The RaPID Platform for the Discovery of Pseudo-Natural Macrocyclic Peptides
2021 · Yuki Goto, Hiroaki Suga · Accounts of Chemical Research · 277
PDF
Site-Specific Nonenzymatic Peptide S/O-Glutamylation Reveals the Extent of Substrate Promiscuity in Glutamate Elimination Domains
2021 · Alexander A. Vinogradov, Masanobu Nagano, et al. · Journal of the American Chemical Society · 20
Posttranslational chemical installation of azoles into translated peptides
2021 · Haruka Tsutsumi, Tomohiro Kuroda, et al. · Nature Communications · 30
PDF
Accurate Broadcasting of Substrate Fitness for Lactazole Biosynthetic Pathway from Reactivity-Profiling mRNA Display
2020 · Alexander A. Vinogradov, Emiko Nagai, et al. · Journal of the American Chemical Society · 28
Promiscuous Enzymes Cooperate at the Substrate Level En Route to Lactazole A
2020 · Alexander A. Vinogradov, Morito Shimomura, et al. · Journal of the American Chemical Society · 38
PDF
Minimal lactazole scaffold for in vitro thiopeptide bioengineering
2020 · Alexander A. Vinogradov, Morito Shimomura, et al. · Nature Communications · 71
PDF
Chemoenzymatic Posttranslational Modification Reactions for the Synthesis of Ψ[CH2NH]‐Containing Peptides
2019 · Yasuharu Kato, Tomohiro Kuroda, et al. · Angewandte Chemie International Edition · 14
Chemoenzymatic Posttranslational Modification Reactions for the Synthesis of Ψ[CH2NH]‐Containing Peptides
2019 · Yasuharu Kato, Tomohiro Kuroda, et al. · Angewandte Chemie · 1
In Vitro Biosynthesis of Peptides Containing Exotic Azoline Analogues
2019 · Yuki Goto, Hiroaki Suga · ChemBioChem · 18
Novel antibiotic screening methods to awaken silent or cryptic secondary metabolic pathways in actinomycetes
2017 · Hiroyasu Onaka · The Journal of Antibiotics · 140
Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo
2017 · Taro Ozaki, Kona Yamashita, et al. · Nature Communications · 84
PDF
Year
Topic