Award

GABAergic Switches Control Wakefulness, NREM sleep and REM sleep

Description: PUBLIC HEALTH RELEVANCE: The proposed research is designed to provide key data regarding the neuronal mechanisms that are responsible for switching between the behavioral states of wakefulness and NREM sleep and REM sleep. In addition, these studies will establish a basis for understanding the pathological mechanisms that are responsible for state-dependent disorders of sleep and wakefulness, such as cataplexy and REM Sleep Behavior Disorder, as well as facilitate the development of efficacious therapies to treat these and related disorders.

Funder: National Institute of Neurological Disorders and Stroke

Funding type: research

Funder scheme: R01

Start date: 2016-04-15

End date: 2023-03-31

Investigator: RONALD SZYMUSIAK

Institution: WEBSCIENCES INTERNATIONAL

Topic: Sleep and Wakefulness Research

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

Funded outputs count: 1

Funder award ID: R01NS092383

OpenAlex ID: G8558536611

Neuronal substrates of sleep homeostasis; lessons from flies, rats and mice

2017 · Jeffrey M Donlea, Md Noor Alam, et al. · Current Opinion in Neurobiology · 56