Pathogenic monocyte response to chronic lung inflammation in cystic fibrosis
Description: PROJECT NARRATIVE Researchers still do not understand the mechanisms behind the progressive and irreversible lung damage that ultimately causes respiratory failure in patients with cystic fibrosis (CF). Our proposed research aims to identify the mechanisms that drive this progressive lung deterioration in CF. Ultimately, our goal is to identify potential therapeutic targets that, in conjunction with the current CFTR modulator therapies, will help prevent progressive lung tissue damage in CF patients.
Funder: National Institutes of Health
Amount: $756,200
Funding type: research
Funder scheme: R01
Start date: 2022-01-01
End date: 2025-11-30
Investigator: EMANUELA MARINA BRUSCIA
Institution: YALE UNIVERSITY
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Funded outputs count: 1
Funder award ID: 5r01hl157776-03
OpenAlex ID: G856411980