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An evidence based algorithm for diagnosis of tuberculosis in HIV patients

Description: Tuberculosis is the leading cause of death in HIV-infected patients in high HIV prevalent countries. A major contributor to death from TB in HIV-infected people is diagnostic delay due to increases in sputum smear negative pulmonary TB and extrapulmonary TB. This project aims to improve the current WHO management algorithm for seriously ill patients admitted to hospital with cough, with the aim of shortening time to diagnosis, increasing diagnostic accuracy and reducing mortality.
Funding type: research
Funder scheme: R01
Start date: 2011-08-11
End date: 2016-07-31
Investigator: GARY MAARTENS
Institution: UNIVERSITY OF CAPE TOWN
Field: Medicine
Funded outputs count: 7
Funder award ID: R01AI096735
OpenAlex ID: G8564978246
Etiology of Pulmonary Infections in Human Immunodeficiency Virus–infected Inpatients Using Sputum Multiplex Real-time Polymerase Chain Reaction
2019 · Gary Maartens, Rulan Griesel, et al. · Clinical Infectious Diseases · 30
Abdominal Ultrasound for the Diagnosis of Tuberculosis Among Human Immunodeficiency Virus-Positive Inpatients With World Health Organization Danger Signs
2019 · Rulan Griesel, Karen Cohen, et al. · Open Forum Infectious Diseases · 16
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Incremental yield and cost of urine Determine TB-LAM and sputum induction in seriously ill adults with HIV
2018 · Tom H. Boyles, Rulan Griesel, et al. · International Journal of Infectious Diseases · 30
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C-reactive protein and procalcitonin to discriminate between tuberculosis, Pneumocystis jirovecii pneumonia, and bacterial pneumonia in HIV-infected inpatients meeting WHO criteria for seriously ill: a prospective cohort study
2018 · Fiona Mendelson, Rulan Griesel, et al. · BMC Infectious Diseases · 41
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Development of a clinical prediction rule to diagnose Pneumocystis jirovecii pneumonia in the World Health Organization’s algorithm for seriously ill HIV-infected patients
2018 · Gary Maartens, Annemie Stewart, et al. · Southern African Journal of HIV Medicine · 15
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Prognostic indicators in the World Health Organization’s algorithm for seriously ill HIV-infected inpatients with suspected tuberculosis
2018 · Rulan Griesel, Annemie Stewart, et al. · AIDS Research and Therapy · 16
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Optimizing Tuberculosis Diagnosis in Human Immunodeficiency Virus–Infected Inpatients Meeting the Criteria of Seriously Ill in the World Health Organization Algorithm
2017 · Rulan Griesel, Annemie Stewart, et al. · Clinical Infectious Diseases · 28
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