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T32 -CA009531

Funded outputs count: 215
Funder award ID: T32 -CA009531
OpenAlex ID: G861968229
Single-nuclei RNA sequencing reveals obesity-associated rewiring of estrogen signaling in endometrioid adenocarcinoma
2026 · Jessica L. Long, Sophia Agrusa, et al. · iScience
DNA Polymerase Beta Catalytic and Fidelity Mutations Drive Platinum-Specific Drug Sensitivity
2026 · Jacob Lindquist, Josh Heyza, et al. · Cancers
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Metastasis suppressing properties of the cell-surface anchored serine protease prostasin: new functional and mechanistic insights from breast cancer
2026 · Joseph G. Lundgren, Michael G. Flynn, et al. · Oncogenesis
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Emerging concepts on one-carbon metabolism as a unique and actionable vulnerability in cancer
2026 · Mathew Schneider, Zhanjun Hou, et al. · ASPET Discovery
The cell-surface serine protease prostasin is lost during cervical squamous cell carcinogenesis
2025 · Joseph G. Lundgren, Michael G. Flynn, et al. · Human Cell · 1
Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumors
2025 · Mathew Schneider, Carrie O’Connor, et al. · Drug Metabolism and Disposition · 2
Overexpression of TSG101 causes the development of adenosquamous mammary carcinoma
2025 · Rayane Dennaoui, Patrick D. Rädler, et al. · Breast Cancer Research · 1
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Social–Environmental Burden Is Associated with Increased Colorectal Cancer Mortality in Metropolitan Detroit
2025 · Natalie G. Snider-Hoy, R. Blake Buchalter, et al. · Cancer Research Communications · 4
Targeting polyunsaturated fatty acids desaturase FADS1 inhibits renal cancer growth via ATF3-mediated ER stress response
2025 · Gioia Heravi, Zhenjie Liu, et al. · Biomedicine & Pharmacotherapy · 10
Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment
2025 · Artem Berezovsky, Oluwademilade Nuga, et al. · PLoS ONE · 6
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Three-Dimensional Models: Biomimetic Tools That Recapitulate Breast Tissue Architecture and Microenvironment to Study Ductal Carcinoma In Situ Transition to Invasive Ductal Breast Cancer
2025 · Seema Shah, Kingsley O. Osuala, et al. · Cells
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GPI-anchored serine proteases: essential roles in development, homeostasis, and disease
2025 · Joseph G. Lundgren, Michael G. Flynn, et al. · Biological Chemistry · 6
Peripheral-derived regulatory T cells contribute to tumor-mediated immune suppression in a nonredundant manner
2024 · Md Moazzem Hossain, Paul King, et al. · Proceedings of the National Academy of Sciences · 10
Role of Mitochondrial and Cytosolic Folylpolyglutamate Synthetase in One-Carbon Metabolism and Antitumor Efficacy of Mitochondrial-Targeted Antifolates
2024 · Carrie O’Connor, Mathew Schneider, et al. · Molecular Pharmacology · 13
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Evaluation of the Immune Response within the Tumor Microenvironment in African American and Non-Hispanic White Patients with Non–Small Cell Lung Cancer
2024 · Matthew R. Trendowski, Donovan Watza, et al. · Cancer Epidemiology Biomarkers & Prevention · 6
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The Janus kinase 1 is critical for pancreatic cancer initiation and progression
2024 · Hridaya Shrestha, Patrick D. Rädler, et al. · Cell Reports · 8
Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer
2024 · Adrianne Wallace-Povirk, Carrie O'Connor, et al. · Molecular Cancer Therapeutics · 15
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Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2
2024 · Jade M. Katinas, Md. Junayed Nayeen, et al. · Biochemistry · 6
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The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia
2024 · Yongwei Su, Jenna L. Carter, et al. · Cancer Research · 21
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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro
2023 · Katie H. Hurrish, Yongwei Su, et al. · Biochemical Pharmacology · 18
Interferon gamma immunoPET imaging to evaluate response to immune checkpoint inhibitors
2023 · Justin B. Hackett, Nicholas Ramos, et al. · Frontiers in Oncology · 5
Cellular Plasticity in Mammary Gland Development and Breast Cancer
2023 · Madison Wicker, Kay-Uwe Wagner · Cancers · 16
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Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria
2023 · Md. Junayed Nayeen, Jade M. Katinas, et al. · Journal of Medicinal Chemistry · 17
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The Role of TRAIL in Apoptosis and Immunosurveillance in Cancer
2023 · Julio M. Pimentel, Jun-Ying Zhou, et al. · Cancers · 114
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Host genetic background regulates the capacity for anti-tumor antibody-dependent phagocytosis
2023 · James E. Glassbrook, Justin B. Hackett, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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