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Optimizing Oil Production in Oleaginous Yeast by Cell-wide Measurements Ans Genome-based Models

Description: OPTIMIZING OIL PRODUCTION IN OLEAGINOUS YEAST BY CELL-WIDE MEASUREMENTS ANS GENOME-BASED MODELS
Amount: $6,683,000
Funding type: grant
Funder scheme: PROJECT GRANT (B)
Start date: 2012-09-01
End date: 2020-02-28
Institution: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Funded outputs count: 15
Funder award ID: DESC0008744
OpenAlex ID: G8819834761
Imaging the competition between growth and production of self-assembled lipid droplets at the single-cell level
2019 · Andreas E. Vasdekis, Hamdah Alanazi, et al. · Optical Methods for Inspection, Characterization, and Imaging of Biomaterials
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Eliciting the impacts of cellular noise on metabolic trade-offs by quantitative mass imaging
2019 · A. E. Vasdekis, H. Alanazi, et al. · Nature Communications · 32
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Impact of forced fatty acid synthesis on metabolism and physiology of Saccharomyces cerevisiae
2018 · Michael Gossing, Agata Smialowska, et al. · FEMS Yeast Research · 16
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Blocking hexose entry into glycolysis activates alternative metabolic conversion of these sugars and upregulates pentose metabolism in Aspergillus nidulans
2018 · Claire Khosravi, Evy Battaglia, et al. · BMC Genomics · 18
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Metabolic engineering of Saccharomyces cerevisiae for overproduction of triacylglycerols
2018 · Raphael Ferreira, Paulo Gonçalves Teixeira, et al. · Metabolic Engineering Communications · 82
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Expression of cocoa genes in Saccharomyces cerevisiae improves cocoa butter production
2018 · Yongjun Wei, David Bergenholm, et al. · Microbial Cell Factories · 39
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Improving the phenotype predictions of a yeast genome‐scale metabolic model by incorporating enzymatic constraints
2017 · Benjamín J Sánchez, Cheng Zhang, et al. · Molecular Systems Biology · 453
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A molecular genetic toolbox for Yarrowia lipolytica
2017 · Erin L. Bredeweg, Kyle R. Pomraning, et al. · Biotechnology for Biofuels · 74
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Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals
2016 · Peng Xu, Kangjian Qiao, et al. · Proceedings of the National Academy of Sciences · 437
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Stability of Ensemble Models Predicts Productivity of Enzymatic Systems
2016 · Matthew K. Theisen, Jimmy G. Lafontaine Rivera, et al. · PLoS Computational Biology · 23
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Regulation of amino-acid metabolism controls flux to lipid accumulation in Yarrowia lipolytica
2016 · Eduard J Kerkhoven, Kyle R Pomraning, et al. · npj Systems Biology and Applications · 202
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Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica
2016 · Andrew M. Silverman, Kangjian Qiao, et al. · Applied Microbiology and Biotechnology · 93
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Multi-omics analysis reveals regulators of the response to nitrogen limitation in Yarrowia lipolytica
2016 · Kyle R. Pomraning, Young-Mo Kim, et al. · BMC Genomics · 103
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Draft Genome Sequence of the Dimorphic Yeast Yarrowia lipolytica Strain W29
2015 · Kyle R. Pomraning, Scott E. Baker · Genome Announcements · 24
An entropy-like index of bifurcational robustness for metabolic systems
2015 · Jimmy G. Lafontaine Rivera, Yun Lee, et al. · Integrative Biology · 7
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