Award

Hhsn272201400021c

Funder: National Institutes of Health

Funded outputs count: 15

Funder award ID: HHSN272201400021C

OpenAlex ID: G8871742542

A Biparatopic Intrabody Renders Vero Cells Impervious to Ricin Intoxication

2024 · Timothy F. Czajka, David J. Vance, et al. · Biochemistry · 1

An ancillary carbohydrate recognition domain on ricin toxin's B subunit is the target of receptor-blocking, neutralizing monoclonal antibodies

2023 · Nicholas Mantis, David Vance, et al.

Sites of vulnerability on ricin B chain revealed through epitope mapping of toxin-neutralizing monoclonal antibodies

2020 · David J. Vance, Amanda Y. Poon, et al. · PLoS ONE · 11

Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin

2020 · Chad J. Roy, Greta Van Slyke, et al. · npj Vaccines · 15

Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site

2020 · Michael J. Rudolph, Timothy F. Czajka, et al. · Journal of Molecular Biology · 19

TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin

2019 · Alexa L. Hodges, Cody G. Kempen, et al. · Toxins · 16

Rescue of rhesus macaques from the lethality of aerosolized ricin toxin

2019 · Chad J. Roy, Dylan J. Ehrbar, et al. · JCI Insight · 28

TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death

2018 · Yinghui Rong, Jennifer Westfall, et al. · mSphere · 11

Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity

2018 · Michael J Rudolph, David J Vance, et al. · Protein Engineering Design and Selection · 9

A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

2017 · Amanda Poon, David Vance, et al. · Toxins · 9

High-Definition Mapping of Four Spatially Distinct Neutralizing Epitope Clusters on RiVax, a Candidate Ricin Toxin Subunit Vaccine

2017 · Ronald T. Toth, Siva Krishna Angalakurthi, et al. · Clinical and Vaccine Immunology · 38

High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin

2017 · David J. Vance, Jacqueline M. Tremblay, et al. · Clinical and Vaccine Immunology · 32

Spatial location of neutralizing and non-neutralizing B cell epitopes on domain 1 of ricin toxin’s binding subunit

2017 · Yinghui Rong, Greta Van Slyke, et al. · PLoS ONE · 17

A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking

2016 · Cristina Herrera, Tove Irene Klokk, et al. · PLoS ONE · 27

Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin’s Enzymatic Subunit Interfere with Intracellular Toxin Transport

2016 · Anastasiya Yermakova, Tove Irene Klokk, et al. · Scientific Reports · 42