The construction and utility of reference pan-genome graphs
Description: PROJECT NARRATIVE The human reference genome sequence is at the heart of all sequence-related biomedical research, such as population genetics, phenotype association, cancer genomics and sequencing based diagnostics and disease treatment. The proposed studies aim to deliver a more complete human reference genome and tools supporting the new representation. The success of this proposal could push the study of complex human variations and their association with diseases to the next level.
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2020-03-01
End date: 2024-02-29
Investigator: HENG LI
Institution: DANA-FARBER CANCER INST
Funded outputs count: 76
Funder award ID: U01HG010961
OpenAlex ID: G8969870