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DK 63947

Funded outputs count: 16
Funder award ID: DK 63947
OpenAlex ID: G9000043987
Targeting senescent cholangiocytes and activated fibroblasts with B‐cell lymphoma‐extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/− ) mice
2017 · Anja Moncsek, Mohammed S. Al‐Suraih, et al. · Hepatology · 135
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Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice
2017 · Maria Eugenia Guicciardi, Anuradha Krishnan, et al. · Cell Death and Disease · 17
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Paving the TRAIL to anti‐fibrotic therapy
2016 · Maria Eugenia Guicciardi, Gregory J. Gores · Hepatology · 5
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Acetaminophen knocks on death's door and receptor interacting protein 1 kinase answers
2015 · Maria Eugenia Guicciardi, Gregory J. Gores, et al. · Hepatology · 1
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Cellular Inhibitor of Apoptosis (cIAP)-Mediated Ubiquitination of Phosphofurin Acidic Cluster Sorting Protein 2 (PACS-2) Negatively Regulates Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Cytotoxicity
2014 · Maria Eugenia Guicciardi, Nathan W. Werneburg, et al. · PLoS ONE · 32
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Pathogenesis of Primary Sclerosing Cholangitis and Advances in Diagnosis and Management
2013 · John E. Eaton, Jayant A. Talwalkar, et al. · Gastroenterology · 436
High Cell Surface Death Receptor Expression Determines Type I Versus Type II Signaling
2011 · Xue Wei Meng, Kevin L. Peterson, et al. · Journal of Biological Chemistry · 30
Death Receptor 5 Internalization Is Required for Lysosomal Permeabilization by TRAIL in Malignant Liver Cell Lines
2009 · Yuko Akazawa, Justin L. Mott, et al. · Gastroenterology · 76
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Life and death by death receptors
2009 · Maria Eugenia Guicciardi, Gregory J. Gores · The FASEB Journal · 690
BH3-only protein mimetic obatoclax sensitizes cholangiocarcinoma cells to Apo2L/TRAIL-induced apoptosis
2008 · Justin L. Mott, Steve F. Bronk, et al. · Molecular Cancer Therapeutics · 42
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Tumor Necrosis Factor-related Apoptosis-inducing Ligand Activates a Lysosomal Pathway of Apoptosis That Is Regulated by Bcl-2 Proteins
2007 · Nathan W. Werneburg, M. Eugenia Guicciardi, et al. · Journal of Biological Chemistry · 126
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Bid Is Upstream of Lysosome-Mediated Caspase 2 Activation in Tumor Necrosis Factor α–Induced Hepatocyte Apoptosis
2005 · M. Eugenia Guicciardi, Steven F. Bronk, et al. · Gastroenterology · 82
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Lysosomes in cell death
2004 · Maria Eugenia Guicciardi, Marcel Leist, et al. · Oncogene · 713
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Arginase: marker, effector, or candidate gene for asthma?
2003 · Donata Vercelli · Journal of Clinical Investigation · 65
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AIP1: a new player in TNF signaling
2003 · M. Eugenia Guicciardi, Gregory J. Gores · Journal of Clinical Investigation · 35
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Arginase: marker, effector, or candidate gene for asthma?
2003 · Donata Vercelli · Journal of Clinical Investigation · 17
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