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GM071862
Funder:
National Institutes of Health
Funded outputs count:
23
Funder award ID:
GM071862
OpenAlex ID:
G9000080098
An intrinsically disordered transcription activation domain increases the DNA binding affinity and reduces the specificity of NFκB p50/RelA
2022
·
Hannah E.R. Baughman
, Dominic Narang
, et al.
·
Journal of Biological Chemistry
·
27
PDF
Multiple Binding Configurations of Fis Protein Pairs on DNA: Facilitated Dissociation versus Cooperative Dissociation
2019
·
Min-Yeh Tsai
, Weihua Zheng
, et al.
·
Journal of the American Chemical Society
·
17
PDF
Prediction of the presence of a seventh ankyrin repeat in IκBε from homology modeling combined with hydrogen–deuterium exchange mass spectrometry (HDX‐MS)
2018
·
Kristen M. Ramsey
, Dominic Narang
, et al.
·
Protein Science
·
7
PDF
Functional importance of stripping in NFκB signaling revealed by a stripping-impaired IκBα mutant
2017
·
Holly E. Dembinski
, Kevin Wismer
, et al.
·
Proceedings of the National Academy of Sciences
·
36
PDF
Structural Basis for the Activation of IKK1/α
2016
·
Smarajit Polley
, Dario Oliveira Passos
, et al.
·
Cell Reports
·
66
A Regulated, Ubiquitin-Independent Degron in IκBα
2015
·
Karen T. Fortmann
, Russell D. Lewis
, et al.
·
Journal of Molecular Biology
·
19
Electrostatics, structure prediction, and the energy landscapes for protein folding and binding
2015
·
Min‐Yeh Tsai
, Weihua Zheng
, et al.
·
Protein Science
·
95
PDF
IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer
2015
·
Rachel Tsui
, Jeffrey D. Kearns
, et al.
·
Nature Communications
·
43
PDF
Predicted disorder-to-order transition mutations in IκBα disrupt function
2014
·
Holly Dembinski
, Kevin Wismer
, et al.
·
Physical Chemistry Chemical Physics
·
25
Correction: Discrete Kinetic Models from Funneled Energy Landscape Simulations
2013
·
Nicholas P. Schafer
, Ryan M. B. Hoffman
, et al.
·
PLoS ONE
PDF
A Structural Basis for Selective Dimerization by NF-κB RelB
2013
·
Don Vu
, De-Bin Huang
, et al.
·
Journal of Molecular Biology
·
22
Discrete Kinetic Models from Funneled Energy Landscape Simulations
2012
·
Nicholas P. Schafer
, Ryan M. B. Hoffman
, et al.
·
PLoS ONE
·
18
Protein frustratometer: a tool to localize energetic frustration in protein molecules
2012
·
M. Jenik
, R. G. Parra
, et al.
·
Nucleic Acids Research
·
148
PDF
Prediction of Native-State Hydrogen Exchange from Perfectly Funneled Energy Landscapes
2011
·
Patricio O. Craig
, Joachim Lätzer
, et al.
·
Journal of the American Chemical Society
·
70
NF-κB Potentiates Caspase Independent Hydrogen Peroxide Induced Cell Death
2011
·
Jessica Q. Ho
, Masataka Asagiri
, et al.
·
PLoS ONE
·
20
PDF
Insights into the regulation of NF-kappaB and mediation of the cellular stress response by NF-kappaB
2010
·
Jessica Q. Ho
·
eScholarship (California Digital Library)
PDF
The Regulatory Logic of the NF- B Signaling System
2009
·
E. O'Dea
, A. Hoffmann
·
Cold Spring Harbor Perspectives in Biology
·
114
PDF
Identifying Critical Non-Catalytic Residues that Modulate Protein Kinase A Activity
2009
·
Eileen J. Kennedy
, Jie Yang
, et al.
·
PLoS ONE
·
19
PDF
The IκBα/NF‐κB complex has two hot spots, one at either end of the interface
2008
·
Simon Bergqvist
, Gourisankar Ghosh
, et al.
·
Protein Science
·
53
PDF
Rapid mass spectrometric analysis of 15N‐Leu incorporation fidelity during preparation of specifically labeled NMR samples
2008
·
Stephanie M.E. Truhlar
, Carla F. Cervantes
, et al.
·
Protein Science
·
8
PDF
Regions of IκBα that are critical for its inhibition of NF-κB·DNA interaction fold upon binding to NF-κB
2006
·
Stephanie M. E. Truhlar
, Justin W. Torpey
, et al.
·
Proceedings of the National Academy of Sciences
·
85
The 20S proteasome processes NF‐κB1 p105 into p50 in a translation‐independent manner
2006
·
Anu K Moorthy
, Olga V Savinova
, et al.
·
The EMBO Journal
·
140
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