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Determinants of immunotherapy response in NASH-Hepatocellular carcinoma

Description: PROJECT NARRATIVE Hepatocellular carcinoma (HCC), the most common type of liver cancer, is a global public health problem. The goal of our proposal is to explore determinants of immunotherapy response in a subgroup of HCCs associated with non-alcoholic steatohepatitis (NASH) that are prone to immune evasion.
Amount: $479,500
Funding type: research
Funder scheme: R01
Start date: 2023-08-04
End date: 2028-07-31
Investigator: JOSEP M LLOVET
Institution: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Funded outputs count: 12
Funder award ID: 5r01ca273932-03
OpenAlex ID: G9000856433
2026 · Josep M. Llovet, Ezequiel Mauro, et al. · Nature Reviews Clinical Oncology · 11
2026 · Mohammad Rahbari, Albert Gris-Oliver, et al. · Nature reviews. Cancer · 3
2026 · Josep M. Llovet, Roser Pinyol, et al. · Cell · 13
2026 · Elena Adan-Villaescusa, Borja Castello-Uribe, et al. · Cell Reports Medicine · 3
2026 · Zhengtao Zhang, Hong Li, et al. · Cancer Cell · 4
2026 · Xin Li, Cynthia Lebeaupin, et al. · Nature · 9
2026 · Anagha Krishna, Alison Meynert, et al. · Nature Genetics · 12
2025 · Ugne Balaseviciute, Júlia Huguet‐Pradell, et al. · Molecular Oncology · 2
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