Investigating the anti-inflammatory mechanisms of calorie restriction in the aged lacrimal gland
Description: Dry eye is a widespread condition that significantly impacts the elderly population globally. Inflammation of the lacrimal gland, responsible for producing aqueous tears, often correlates with aging. This proposal aims to elucidate the cellular and molecular mechanisms underlying calorie restriction and explore its impact on progenitor cell function and gland regeneration.
Funder: National Eye Institute
Funding type: research
Funder scheme: R01
Start date: 2024-06-01
End date: 2029-02-28
Investigator: CINTIA S. DE PAIVA
Institution: SCRIPPS RESEARCH INSTITUTE, THE
Funded outputs count: 9
Funder award ID: R01EY035333
OpenAlex ID: G9000856439