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Characterization of in vivo neuronal and inter-neuronal responses to transcranial focused ultrasound

Description: We propose to investigate the in vivo neuronal cell-type specific response and long-term plasticity effects of transcranial focused ultrasound neuromodulation in both anesthetized and awake animal models. The project promises to better understand the biological and biophysical mechanisms of an important noninvasive neuromodulation technology that may eventually be used to treat patients with a variety of brain disorders.
Amount: $571,100
Funding type: research
Funder scheme: RF1
Start date: 2021-09-25
End date: 2026-08-31
Investigator: BIN HE
Institution: CARNEGIE-MELLON UNIVERSITY
Funded outputs count: 11
Funder award ID: 4rf1ns124564-02
OpenAlex ID: G9000856477
2026 · Sandhya Ramachandran, Huan Gao, et al. · Microsystems & Nanoengineering
2026 · Yidan Ding, Maxim Karrenbach, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2026 · Yidan Ding, Joshua Kosnoff, et al. · Trends in Neurosciences · 1
2026 · Joshua Kosnoff, Joseph Zhang, et al. · IEEE Transactions on Neural Systems and Rehabilitation Engineering
2025 · Huan Gao, Annabel Frake, et al. · IEEE Transactions on Neural Systems and Rehabilitation Engineering · 3
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