Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related Meningitis
Description: 8. Project Narrative In Africa, meningitis ranks second among HIV/AIDS defining illnesses, contributing approximately 15- 20% of AIDS-related mortality. Historically, Cryptococcus and TB were the two most common causes of meningitis in Africa. However, with the widespread rollout of HIV therapy, the epidemiological landscape is likely shifting. This project aims to define the current epidemiology, validate novel diagnostic tests, and carry out a mechanistic proof-of-concept trial for a new antifungal drug to treat fungal meningitis.
Funding type: research
Funder scheme: R01
Start date: 2013-09-01
End date: 2029-05-31
Investigator: DAVID R BOULWARE
Institution: UNIVERSITY OF MINNESOTA
Funded outputs count: 170
Funder award ID: R01NS086312
OpenAlex ID: G9000876216