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R01HL137030
Funder:
National Heart, Lung, and Blood Institute
Funded outputs count:
40
Funder award ID:
R01HL137030
OpenAlex ID:
G920798299
Spatiotemporal calcium signaling patterns underlying opposing effects of histamine and TAS2R agonists in airway smooth muscle
2025
·
Stanley Conaway
, Joshua Richard
, et al.
·
American Journal of Physiology-Lung Cellular and Molecular Physiology
·
4
A-Kinase–Anchoring Protein Subtypes Differentially Regulate GPCR Signaling and Function in Human Airway Smooth Muscle
2024
·
Elham Javed
, Ajay P. Nayak
, et al.
·
American Journal of Respiratory Cell and Molecular Biology
·
2
PDF
Molecular mechanism of bitter taste receptor agonist‐mediated relaxation of airway smooth muscle
2024
·
Stanley Conaway
, Weiliang Huang
, et al.
·
The FASEB Journal
·
15
Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca2+ Signaling in Airway Smooth Muscle
2023
·
Deepak A. Deshpande
, Raymond B. Penn
·
American Journal of Respiratory Cell and Molecular Biology
Comparing Performance of Spectral Image Analysis Approaches for Detection of Cellular Signals in Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy
2023
·
Marina Parker
, Naga S. Annamdevula
, et al.
·
Bioengineering
·
8
PDF
Combined hyperspectral imaging, monolayer stress microscopy, and S8 image analysis approaches for simultaneously interrogating cellular signals and biomechanics
2023
·
Silas J. Leavesley
, Santina Johnson
, et al.
PDF
In silico identification of a β 2 -adrenoceptor allosteric site that selectively augments canonical β 2 AR-Gs signaling and function
2022
·
Sushrut D. Shah
, Christoffer Lind
, et al.
·
Proceedings of the National Academy of Sciences
·
26
Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma
2022
·
Miguel Angel Hernandez-Lara
, Santosh K. Yadav
, et al.
·
International Journal of Molecular Sciences
·
13
PDF
Targeted Inhibition of Select Extracellular Signal-regulated Kinases 1 and 2 Functions Mitigates Pathological Features of Asthma in Mice
2022
·
Sushrut D. Shah
, Ajay P. Nayak
, et al.
·
American Journal of Respiratory Cell and Molecular Biology
·
16
Microscopy is better in color: development of a streamlined spectral light path for real-time multiplex fluorescence microscopy
2022
·
Craig M. Browning
, Samantha Mayes
, et al.
·
Biomedical Optics Express
·
5
Measurement of agonist-induced Ca2+ signals in human airway smooth muscle cells using excitation scan-based hyperspectral imaging and image analysis approaches
2022
·
Santina Johnson
, D. J. Pleshinger
, et al.
Hyperspectral imaging and adaptive thresholding to identify agonist-induced cAMP signals in pulmonary microvascular endothelial cells
2022
·
Naga S. Annamdevula
, Santina Johnson
, et al.
·
1
Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling
2021
·
Pawan Sharma
, Santosh K. Yadav
, et al.
·
American Journal of Respiratory Cell and Molecular Biology
·
18
Autocrine regulation of airway smooth muscle contraction by diacylglycerol kinase
2021
·
Santosh K. Yadav
, Pawan Sharma
, et al.
·
Journal of Cellular Physiology
·
12
Chloroquine: Autophagy inhibitor, antimalarial, bitter taste receptor agonist in fight against COVID-19, a reality check?
2021
·
Pawan Sharma
, Kielan D. McAlinden
, et al.
·
European Journal of Pharmacology
·
21
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR
2020
·
Jessie Huang
, Hong Lam
, et al.
·
Proceedings of the National Academy of Sciences
·
26
Milestones in the development and implementation of FRET-based sensors of intracellular signals: A biological perspective of the history of FRET
2020
·
J. Deal
, D.J. Pleshinger
, et al.
·
Cellular Signalling
·
33
Therapeutic potential and challenges of bitter taste receptors on lung cells
2020
·
Stanley Conaway
, Ajay P Nayak
, et al.
·
Current Opinion in Pharmacology
·
18
Spectral illumination system utilizing spherical reflection optics
2020
·
Samantha Gunn Mayes
, Craig M. Browning
, et al.
Comparison of spectral FRET microscopy approaches for single-cell analysis
2020
·
Joshua Deal
, Naga S. Annamdevula
, et al.
·
1
Bnip3 regulates airway smooth muscle cell focal adhesion and proliferation
2019
·
Shi Pan
, Sushrut D. Shah
, et al.
·
American Journal of Physiology-Lung Cellular and Molecular Physiology
·
24
Bitter Taste Receptors: an Answer to Comprehensive Asthma Control?
2019
·
Ajay P. Nayak
, Dominic Villalba
, et al.
·
Current Allergy and Asthma Reports
·
18
Excitation-Scanning Hyperspectral Imaging Microscopy to Efficiently Discriminate Fluorescence Signals
2019
·
Joshua Deal
, Andrea Britain
, et al.
·
Journal of Visualized Experiments
·
13
Bitter Taste Receptors for Asthma Therapeutics
2019
·
Ajay P. Nayak
, Sushrut D. Shah
, et al.
·
Frontiers in Physiology
·
62
PDF
Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle
2019
·
Tonio Pera
, Eric Tompkins
, et al.
·
The FASEB Journal
·
10
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