Connecting Polycystin Signaling to Asymmetric Nodal Expression
Description: The proposed research is relevant to public heath because our identification of the signaling pathways involved in establishing left-right patterning will provide important new targets to investigate as factors underlying congenital heart disease (CHD). As surgical intervention improves, there is a growing need to identify the important causative factors for CHD, so that adults born with CHD can receive appropriate health care and proper testing to determine their risk of having a child with CHD. Thus, the proposed research is relevant to the NIH's mission to develop the fundamental knowledge needed to extend healthy life and reduce the burdens of illness.
Funding type: research
Funder scheme: R01
Start date: 2007-02-15
End date: 2017-04-30
Investigator: REBECCA D. BURDINE
Institution: PRINCETON UNIVERSITY
Subfield: Genetics
Domain: Life Sciences
Funded outputs count: 30
Funder award ID: R01HD048584
OpenAlex ID: G978206172