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Esperion Therapeutics (United States)

Homepage: esperion.com
ROR: 019f2k932
OpenAlex ID: I25764616
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients
2023 · Steven E. Nissen, A. Michael Lincoff, et al. · New England Journal of Medicine · 972
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Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol
2019 · Kausik K. Ray, Harold E. Bays, et al. · New England Journal of Medicine · 806
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Aromaticity as a Cornerstone of Heterocyclic Chemistry
2004 · Alexandru T. Balaban, Daniela C. Oniciu, et al. · Chemical Reviews · 805
Methionine‐deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF‐I and insulin levels, and increases hepatocyte MIF levels and stress resistance
2005 · Richard A. Miller, Gretchen Buehner, et al. · Aging Cell · 734
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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
2016 · Stephen L. Pinkosky, Roger S. Newton, et al. · Nature Communications · 494
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Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease
2019 · Anne C. Goldberg, Lawrence A. Leiter, et al. · JAMA · 481
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Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance
2019 · Ulrich Laufs, Maciej Banach, et al. · Journal of the American Heart Association · 433
Efficacy and safety of bempedoic acid added to ezetimibe in statin-intolerant patients with hypercholesterolemia: A randomized, placebo-controlled study
2018 · Christie M. Ballantyne, Maciej Banach, et al. · Atherosclerosis · 423
Lipogenesis inhibitors: therapeutic opportunities and challenges
2022 · Battsetseg Batchuluun, Stephen L. Pinkosky, et al. · Nature Reviews Drug Discovery · 399
Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy
2019 · Christie M Ballantyne, Ulrich Laufs, et al. · European Journal of Preventive Cardiology · 359
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Cardiovascular Status of Carriers of the Apolipoprotein A-I Milano Mutant
2001 · Cesare R. Sirtori, Laura Calabresi, et al. · Circulation · 322
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Statin Intolerance and Risk of Coronary Heart Events and All-Cause Mortality Following Myocardial Infarction
2017 · Maria-Corina Serban, Lisandro D. Colantonio, et al. · Journal of the American College of Cardiology · 320
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Quantitative Measures of Aromaticity for Mono-, Bi-, and Tricyclic Penta- and Hexaatomic Heteroaromatic Ring Systems and Their Interrelationships
2001 · Alan R. Katritzky, Karl Jug, et al. · Chemical Reviews · 307
AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases
2012 · Rai Ajit K. Srivastava, Stephen L. Pinkosky, et al. · Journal of Lipid Research · 296
Metabolomics applications of FT‐ICR mass spectrometry
2004 · Stephen C. Brown, Gary Kruppa, et al. · Mass Spectrometry Reviews · 286
AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism
2012 · Stephen L. Pinkosky, Sergey Filippov, et al. · Journal of Lipid Research · 239
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Increased Atherosclerosis in ApoE and LDL Receptor Gene Knock-Out Mice as a Result of Human Cholesteryl Ester Transfer Protein Transgene Expression
1999 · Andrew S. Plump, Lori Masucci-Magoulas, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 221
Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
2022 · Marisa R. Morrow, Battsetseg Batchuluun, et al. · Cell Metabolism · 196
Recombinant Apolipoprotein A-I Milano Infusion Into Rabbit Carotid Artery Rapidly Removes Lipid From Fatty Streaks
2002 · Giulia Chiesa, Elena Monteggia, et al. · Circulation Research · 194
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Association of Bempedoic Acid Administration With Atherogenic Lipid Levels in Phase 3 Randomized Clinical Trials of Patients With Hypercholesterolemia
2020 · Maciej Banach, P. Barton Duell, et al. · JAMA Cardiology · 187
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Efficacy and Safety of a Novel Dual Modulator of Adenosine Triphosphate-Citrate Lyase and Adenosine Monophosphate-Activated Protein Kinase in Patients With Hypercholesterolemia
2013 · Christie M. Ballantyne, Michael H. Davidson, et al. · Journal of the American College of Cardiology · 175
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Efficacy and Safety of ETC-1002, a Novel Investigational Low-Density Lipoprotein-Cholesterol–Lowering Therapy for the Treatment of Patients With Hypercholesterolemia and Type 2 Diabetes Mellitus
2014 · Maria J. Gutierrez, Noah L. Rosenberg, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 170
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Mouse Macrophage Paraoxonase 2 Activity Is Increased Whereas Cellular Paraoxonase 3 Activity Is Decreased Under Oxidative Stress
2003 · Mira Rosenblat, Dragomir Draganov, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 167
Use of ETC-1002 to treat hypercholesterolemia in patients with statin intolerance
2015 · Paul D. Thompson, John Rubino, et al. · Journal of clinical lipidology · 159
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Inflammation and Cholesterol as Predictors of Cardiovascular Events Among 13 970 Contemporary High-Risk Patients With Statin Intolerance
2023 · Paul M Ridker, Lei Lei, et al. · Circulation · 146
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Works count: 198
Citation count: 50,170
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