National Center for Drug Screening

Homepage: screen.org.cn

Alternate name: 国家新药筛选中心

ROR: 0384ghs60

OpenAlex ID: I4210126186

The Arabidopsis CORONATINE INSENSITIVE1 Protein Is a Jasmonate Receptor

2009 · Jianbin Yan, Chi Zhang, et al. · The Plant Cell · 792

Common activation mechanism of class A GPCRs

2019 · Qingtong Zhou, Dehua Yang, et al. · eLife · 633

G protein-coupled receptors: structure- and function-based drug discovery

2021 · Dehua Yang, Qingtong Zhou, et al. · Signal Transduction and Targeted Therapy · 632

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Small molecule regulators of autophagy identified by an image-based high-throughput screen

2007 · Lihong Zhang, Jia Yu, et al. · Proceedings of the National Academy of Sciences · 470

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Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes

2016 · Chris de Graaf, Dan Donnelly, et al. · Pharmacological Reviews · 400

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Structure of the human glucagon class B G-protein-coupled receptor

2013 · Fai Yiu Siu, Min He, et al. · Nature · 379

Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in China

2009 · Kui Hong, An-Hui Gao, et al. · Marine Drugs · 371

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The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

2017 · Bo Shan, Xiaoxia Wang, et al. · Nature Immunology · 367

Small-molecule fluorescence-based probes for interrogating major organ diseases

2021 · Hai-Hao Han, He Tian, et al. · Chemical Society Reviews · 366

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A systematic analysis of FDA-approved anticancer drugs

2017 · Jingchun Sun, Qiang Wei, et al. · BMC Systems Biology · 322

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Tools for GPCR drug discovery

2012 · Ru Zhang, Xin Xie · Acta Pharmacologica Sinica · 317

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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex

2018 · Yi-Lynn Liang, Maryam Khoshouei, et al. · Nature · 315

Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways

2011 · Fei Xiao, Zhiying Huang, et al. · Diabetes · 286

Molecular recognition of morphine and fentanyl by the human μ-opioid receptor

2022 · Youwen Zhuang, Yue Wang, et al. · Cell · 274

Fluorescent probes for the detection of disease-associated biomarkers

2022 · Wei-Tao Dou, Hai-Hao Han, et al. · 中国科学通报：英文版 · 266

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Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake

2006 · Wei Zhang, Di Hong, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 264

Fluorescent probes for the imaging of lipid droplets in live cells

2020 · He Tian, Adam C. Sedgwick, et al. · Coordination Chemistry Reviews · 251

Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails

2015 · Yanbin Fu, Chenwen Huang, et al. · Cell Research · 249

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Selective Late‐Stage Oxygenation of Sulfides with Ground‐State Oxygen by Uranyl Photocatalysis

2019 · Yiming Li, S. Aal‐e‐Ali Rizvi, et al. · Angewandte Chemie International Edition · 246

Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK

2006 · Zhe Cheng, Tao Pang, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 240

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

2017 · Gaojie Song, Dehua Yang, et al. · Nature · 239

Insights into the structure of class B GPCRs

2013 · Kaspar Hollenstein, Chris de Graaf, et al. · Trends in Pharmacological Sciences · 239

Microstructure, mechanical properties, biocompatibility, and in vitro corrosion and degradation behavior of a new Zn–5Ge alloy for biodegradable implant materials

2018 · Xian Tong, Dechuang Zhang, et al. · Acta Biomaterialia · 219

Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications

2021 · Luling Wu, Jihong Liu, et al. · Journal of the American Chemical Society · 213

Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees

2011 · Astrid Spannhoff, Yong Kee Kim, et al. · EMBO Reports · 212

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Works count: 992

Citation count: 145,300