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Evotec (Germany)

Homepage: evotec.com
ROR: 03d3v3e93
OpenAlex ID: I4210130816
Natural products in drug discovery: advances and opportunities
2021 · Atanas G. Atanasov, Sergey B. Zotchev, et al. · Nature Reviews Drug Discovery · 5,401
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Amide bond formation and peptide coupling
2005 · Christian A.G.N. Montalbetti, Virginie Falque · Tetrahedron · 1,786
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
2021 · Eliza Yankova, Wesley Blackaby, et al. · Nature · 1,356
Alternatives to antibiotics—a pipeline portfolio review
2016 · Lloyd Czaplewski, Richard Bax, et al. · The Lancet Infectious Diseases · 848
Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution
1997 · P. Schwille, F.J. Meyer-Almes, et al. · Biophysical Journal · 817
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Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005 · James N. C. Kew, John A. Kemp · Psychopharmacology · 789
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology
2019 · Claire Bridel, Wessel N. van Wieringen, et al. · JAMA Neurology · 753
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Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome
2002 · Joanna Groom, Susan L. Kalled, et al. · Journal of Clinical Investigation · 713
Minisci reactions: Versatile CH-functionalizations for medicinal chemists
2011 · Matthew A. J. Duncton · MedChemComm · 607
NMDA receptor pathways as drug targets
2002 · John A. Kemp, Ruth M. McKernan · Nature Neuroscience · 476
Fluorescence-intensity distribution analysis and its application in biomolecular detection technology
1999 · Peet Kask, Kaupo Palo, et al. · Proceedings of the National Academy of Sciences · 455
Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
2016 · Peter Langfelder, Jeffrey P Cantle, et al. · Nature Neuroscience · 405
GDC-0449—A potent inhibitor of the hedgehog pathway
2009 · Kirk D. Robarge, Shirley A. Brunton, et al. · Bioorganic & Medicinal Chemistry Letters · 386
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction
2019 · Roman C. Hillig, Brice Sautier, et al. · Proceedings of the National Academy of Sciences · 375
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Accurate calculation of the absolute free energy of binding for drug molecules
2015 · Matteo Aldeghi, Alexander Heifetz, et al. · Chemical Science · 347
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SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration
2021 · Matthew D. Figley, Weixi Gu, et al. · Neuron · 322
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Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease
2014 · Zuzana Šišková, Daniel Justus, et al. · Neuron · 319
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Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila
2004 · Isabell Greeve, Doris Kretzschmar, et al. · Journal of Neuroscience · 287
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Identification and characterization of novel TRPV4 modulators
2009 · Fabien Vincent, Alejandra Acevedo, et al. · Biochemical and Biophysical Research Communications · 246
A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders
2008 · J.D.A. Olivier, M.G.C. Van Der Hart, et al. · Neuroscience · 246
MaxDIA enables library-based and library-free data-independent acquisition proteomics
2021 · Pavel Sinitcyn, Hamid Hamzeiy, et al. · Nature Biotechnology · 244
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A 3-D microelectrode system for handling and caging single cells and particles
1999 · T. Müller, G. Gradl, et al. · Biosensors and Bioelectronics · 242
Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism
2013 · Douglas Marcotte, Weike Zeng, et al. · Bioorganic & Medicinal Chemistry · 239
Microdevices for manipulation and accumulation of micro‐ and nanoparticles by dielectrophoresis
2003 · Manfried Dürr, Jörg Kentsch, et al. · Electrophoresis · 235
Glutamate- and GABA-based CNS therapeutics
2005 · A FOSTER, J KEMP · Current Opinion in Pharmacology · 213
Works count: 620
Citation count: 45,650
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